Arachidonic Acid and Prostaglandins

Triethanolamine has been clinically tested with other model irritant compoimds for potency to stimulate signal release of proinflammatory mediators in hrnnan skin in order to find biomarkers of irritancy. Neat or aqueous triethanolamine was applied to the lower arm of 12 male volimteers after 24 h, suction blister fluid specimens were taken from the site of treated skin. Triethanolamine caused no significant increase in arachidonic acid and prostaglandin concentrations in suction blister fluid samples, in... [Pg.390]

With regard to other effects of palytoxin on metabolism, it is interesting to mention that palytoxin has been reported to stimulate both metabolism of arachidonic acid and prostaglandin production [65]. These properties are thought to be related with palytoxin s tumor-promoting activity, as palytoxin is a known non-TPA-type tumor promoter [66],... [Pg.640]

Gerritsen, M.E. and Cheli, C.D. (1983). Arachidonic acid and prostaglandin endoperoxide metabolism in isolated rabbit and coronary microvessels and isolated and cultivated coronary microvessel endothelial cells. ]. Clin. Invest., 72, 1658-1671... [Pg.30]

Weber, P.C., Larsson, C., Anggard, E., Hamberg, M., Corey, E.J., Nicolaou, K.C. and Samuelsson, B. (1976). Stimulation of renin release from rabbit renal cortex by arachidonic acid and prostaglandin endoperoxides. Circ. Res., 39, 868-874... [Pg.33]

Wlodawer, P., Kindahl, H. and Hamberg, M. (1976). Biosynthesis of prostaglandin F2 from arachidonic acid and prostaglandin endoperoxides in the uterus. Biochim. Biophys. Acta, 431, 603-614... [Pg.242]

Bosisio E, Galli C, Galli G, Nicosia S, Spagnuolo C, Tosi L Correlation between release of free arachidonic acid and prostaglandin formation in brain cortex and cerebellum. Rrostaglandins 11(5) 773-781, 1978. [Pg.70]

Stoll, K. E., Ottino, P., and Duncan, J. R., 1994, Interrelationship of ascorbate, arachidonic acid and prostaglandin E2 in B16 melanoma cells. Prostaglandins Leukotrienes Essential Fatty Acids 50 123-131. [Pg.116]

Andreis, P.G., Whitfield, J.F. and Armato, U. (1981) Simulation of DNA synthesis and mitosis of hepatocytes in primary cultures of neonatal rat liver by arachidonic acid and prostaglandins. Exp. Cell Res. 134, 265-272. [Pg.353]

Compare the structures and functional groups of arachidonic acid and prostaglandin POE]. [Pg.519]

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