Applications of Chemical Microarrays

Chemical microarrays are used extensively in both basic science and apphed science applications. 

Synthesis Less efficient (except for light- directed synthesis methods, which are more efficient but restricted to peptides or peptoids) Highly efficient using the split synthesis method 

Compound arrangement Spatially separable on a two-dimensional array Spatially separable on beads (beads in suspension or immobilized on solid support or in soft agar) 

Number of compounds Hundreds to a few thousands Thousands to a few millions 

Screening methods Mostly on-slide screening, solution phase assay also possible Mostly on-bead screening, solution phase assay also possible 

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Below is a brief description of various applications of chemical microarrays, with a focns on peptide/peptidomimetics, small molecule, and carbohydrate... 

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