Applications infarction

Meticulous care needs to be used in the application of this tissue adhesive. Only a very thin layer of adhesive should be used to assist with reapproximation of the intima and adventitia. It is important to remember that the material should not be allowed to drip into or onto critical areas such as the ostium of the coronary arteries. Inadvertent placement of this agent in such areas can result in blockage of a critical artery and a potentially fatal myocardial infarction. In addition. 

In situations where inappropriate clot formation results in the blockage of a blood vessel, the tissue damage that ensues depends, to a point, upon how long the clot blocks blood flow. Rapid removal of the clot can often minimize the severity of tissue damage. Thus, several thrombolytic (clot-degrading) agents have found medical application (Table 12.5). The market for an effective thrombolytic agent is substantial. In the USA alone, it is estimated that 1.5 million people suffer acute myocardial infarction each year, and there are another 0.5 million suffer strokes. 

Brain infarction was the first clinical application of SPECT. Decreases in relative cerebral perfusion were imaged by SPECT for diagnosis. Decreased rCBF is visualized in the form of decreased signal on SPECT and PET. The sensitivity and specificity of brain SPECT for infarct localization are 85.5% and 97.6%, respectively [99]. Blood-flow imaging is useful in the evaluation of response to therapy in patients with cerebrovascular diseases [100]. 

G. Other applications Lepirudin is also under study for the treatment of myocardial infarction and unstable angina and other thromboembolic disorders requiring parenteral antithrombotic therapy such as disseminated intravascular coagulation, in adults. 

G. Other applications In combination with streptokinase, Integrilin improved coronary patency in patients experiencing an acute myocardial infarction but had no effect on clinical outcome and increased the rate of bleeding. 

G. Other applications In patients with acute myocardial infarction, coronary stenting plus ReoPro leads to a greater degree of myocardial salvage and a better clinical outcome than does fibrinolysis with a tissue plasminogen activator. As compared with placebo, early administration of ReoPro in patients with acute myocardial infarction improves coronary patency before stenting, the success rate of the... 

Myocardial infarction -thrombolytic therapy [ENZYME APPLICATIONS - THERAPEUTIC] (Vol 9)... 

Disturbances of proton diffusion are not unique to cerebral ischemia. Reduced diffusion has also been found in various experimental conditions including spreading depression (Busch et al. 1995) and peri-infarct depolarizations (Gyngell et al. 1994 Rother et al. 1996), hypoglycemia (Hasegawa et al. 1996), following cortical application of noxious substances [blockers of the Na+-/K+-ATPase (Benveniste et al. 1992), excitotoxins (Verheul et al. 1994)] and... 

Mokri B (2001) The Monro-Kellie hypothesis applications in CSF volume depletion. Neurology 56 1746-1748 Naruse S, Horikawa Y, Tanaka C, Hirakawa K, Nishikawa H, Yoshizaki K (1982) Proton nuclear magnetic resonance studies on brain edema. J Neurosurg 56 747-752 Nedergaard M, Vorstrup S, Astrup J (1986) Cell density in the borderzone around old small human brain infarcts. Stroke 17 1129-1137... 

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