Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Antiulcer agents

The market for antiulcer agents (Fig. 1) is large and is comprised of both prescription and over the counter (OTC) products. The estimated prescription market is over 3 biUion aimuaHy in the United States, whereas the more difficult to estimate OTC market is in the range of 500 million aimuaHy. Several pharmaceutical companies are attempting to obtain approval for OTC use of prescription-only agents, and patent protection for several of the histamine antagonists mns out in the mid-1990s. [Pg.198]

The antiulcer agent rebamipide ((2-(4-chlorobenzoy-lamino)-3-[2(lH)-quinolinon-4-yl]propionic acid) dose-dependently decreased hydroxyl radical signal generated by the Fenton reaction in an e.s.r. study. Rebamipide is active as a hydroxyl radical scavenger and inhibitor of superoxide production by neutrophils (Yoshikawa etal., 1993). [Pg.272]

The total synthesis of the novel, potent antiulcer agent... [Pg.352]

Rabeprazole (AcipHex) [Antiulcer Agent/Proton Pump Inhibitor] Uses PUD, GERD, ZE H. pylori Action Proton pump inhibitor Dose 20 mg/d may T to 60 mg/d H. pylori 20 mg PO bid X 7 d (w/ amoxicillin and clarithromycin) do not crush/chew tabs Caution [B, /—] Disp Tabs SE HA, fatigue, GI upset Interactions t Effects OF cyclosporine, digoxin -1- effects OF ketoconazole EMS None OD May cause N, tach, dry mouth, and drowsiness symptomatic and supportive... [Pg.271]

Mechanism of Action An antinauseant and antiulcer agent that absorbs water and toxins in the large intestine and forms a protective coating in the intestinal mucosa. Also possesses antisecretory and antimicrobial effects. Therapeutic Effect Prevents diarrhea. Helps treat Helicobacter pybri-associated peptic ulcer disease. [Pg.143]

Mechanism of Action A tricyclic antidepressant, antianxiety agent, antineuralgic agent, antipruritic, and antiulcer agent that increases synaptic concentrations of norepinephrine and serotonin. TIicrapcuticEffect Produces antidepressant and anxiolytic effects. [Pg.399]

Mechanism of Action An antiulcer agent that forms an ulcer-adherent complex with proteinaceous exudate, such as albumin, at ulcer site. Also forms a viscous, adhesive barrier on the surface of intact mucosa of the stomach or duodenum. Therapeutic Effect Protects damaged mucosa from further destruction by absorbing gastric acid, pepsin, and bile salts. [Pg.1154]

As discussed earlier, receptors are responsible for histamine induced gastric acid secretion. H -receptors antagonists such as cimetidine, ranitidine, famotidine etc. are used in the treatment of peptic ulcer and are discussed in chapter Antiulcer agents. ... [Pg.219]

Antacids and Antiulcer Agents Section 8 Drugs Acting on Endocrine System 261... [Pg.500]

Federsel, H.-J. and Larsson, M. An Innovative Asymmetric Sulfide Oxidation The Process Development History behind the New Antiulcer Agent Esomeprazole in Asymmetric Catalysis on Industrial Scale, Blaser, H.U. and Schmidt, E. (Eds). Wiley-VCH New York, 2004, 413 36. [Pg.33]

See other pages where Antiulcer agents is mentioned: [Pg.198]    [Pg.199]    [Pg.385]    [Pg.260]    [Pg.10]    [Pg.1142]    [Pg.206]    [Pg.215]    [Pg.256]    [Pg.288]    [Pg.289]    [Pg.276]    [Pg.40]    [Pg.41]    [Pg.72]    [Pg.1358]    [Pg.49]    [Pg.272]    [Pg.291]    [Pg.674]    [Pg.675]    [Pg.54]    [Pg.103]    [Pg.261]    [Pg.262]    [Pg.263]    [Pg.265]    [Pg.460]    [Pg.361]    [Pg.677]    [Pg.88]    [Pg.278]    [Pg.70]    [Pg.48]    [Pg.291]   
See also in sourсe #XX -- [ Pg.256 ]

See also in sourсe #XX -- [ Pg.48 ]

See also in sourсe #XX -- [ Pg.54 , Pg.103 , Pg.120 , Pg.448 , Pg.449 ]

See also in sourсe #XX -- [ Pg.48 ]

See also in sourсe #XX -- [ Pg.71 ]

See also in sourсe #XX -- [ Pg.109 ]

See also in sourсe #XX -- [ Pg.2 , Pg.47 ]

See also in sourсe #XX -- [ Pg.48 ]



SEARCH



Antiulcer

Antiulcerative

Antiulcers

© 2024 chempedia.info