Antitumor activity of polysaccharide

Zhang, . P., X. Y. Lu, P. C. Ma, Y. Chen, Y. G. Zhang, and Z. Yan. 1993. Studies on diterpenoids from leaves of Tripterygium wilfordii. Acta Pharm. Sin. 28 110-115. Wang, J. Z., H. Tsumura, K. Shimura, and H. Ito. 1992. Antitumor activity of polysaccharide from a Chinese medicinal herb, Acanthopanax giraldii Harms. Cancer Lett. 65 79-84. 

Adams and coworkers21 also examined the chemical composition and antitumor activity of polysaccharide fractions obtained from the Temple University strain of S. marcescens grown in a medium containing sucrose. Some fractions were obtained from bacterial cells by repeated extraction with aqueous phenol, followed by digestion with... 

Zhuang, C., Mizuno, T., Ito, H., and Shimura, K., Chemical modification and antitumor activity of polysaccharides from the mycelium of liquid-cultured Grifola frondosa, Nippon Shokuhin Kogyo Gakkaishi, 41, 733-740, 1994. 

T. Ikekawa, Y. Ikeda, and F. Tukuoka, Antitumor activity of polysaccharides from Serratia marcescens, Gann, 66 (3), 317-318,1975. 

Q. Huang, Y. Jin, L. Zhang, P.C.K. Cheung, J.E Kennedy, Structure, molecular size and antitumor activities of polysaccharides from Poria cocos mycelia produced in fermenter, Carbohydr. Pol, 70.324-333, 2007. 

Enzymes Degrading Macromolecules. Enzymes that degrade macromolecules such as membrane polysaccharides, stmctural and functional proteins, or nucleic acids, have all shown oncolytic activity. Treatment strategies include the treatment of inoperable tumors with pepsin (1) antitumor activity of carboxypeptidase (44) cytotoxicity of ribonudease (45—47) oncolytic activity of neuraminidase (48—52) therapy with neuraminidase of patients with acute myeloid leukemia (53) antitumor activity of proteases (54) and hyaluronidase treatment in the management of human soHd tumors (55). 

Chen R, meng F, Liu Z, Chen R, Zhang M. Antitumor activities of different fractions of polysaccharide purified from Ornithogalum caudatum Ait. Carbohydrate Polymers 2010 80 845-851. 

Antitumor Activity of Yeast Polysaccharides Against Subcutaneously Implanted Sarcoma 180 in Mice"... 

Properties and Antitumor Activity of Some Polysaccharides Containing Mainly (1 — 6)-Linkages... 

Peng Y, Zhang L, Zeng F, et al. (2005). Structure and antitumor activities of the water-soluble polysaccharides from Ganoderma tsugae mycelium. Carbohyd. Polym. 59 385-392. 

Yoo S-H, Yoon E J, Cha J, et al. (2004). Antitumor activity of levan polysaccharides from selected microorganisms. Internat. J. Biol. Macromol. 34 37-41. 

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