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Antisense oligonucleotides complications

Antisense Oligonucleotides. Table 2 Viral disorders with malignant complications as potential targets for ribozyme gene therapies... [Pg.188]

In conclusion, phosphorothioate oligonucleotides may interact with a wide range of proteins through several types of mechanisms. These interactions may influence the pharmacokinetic, pharmacologic, and toxicologic properties of these molecules. They may also complicate studies on the mechanism of action of these drugs, and may obscure an antisense activity. For example, phosphorothio-... [Pg.131]

See other pages where Antisense oligonucleotides complications is mentioned: [Pg.26]    [Pg.780]    [Pg.1898]    [Pg.122]    [Pg.1096]    [Pg.398]    [Pg.205]    [Pg.122]    [Pg.122]    [Pg.122]    [Pg.332]    [Pg.415]    [Pg.1611]    [Pg.17]   
See also in sourсe #XX -- [ Pg.373 ]



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Antisense oligonucleotides

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