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Antinematodal agents

VinyIpyridine (26) exhibits many of the properties of a Michael acceptor. Thus, this molecule will undergo conjugate addition of methoxide ion. There is thus obtained methyridine (27), an antinematodal agent used in veterinary practice. [Pg.256]

Erythromycin, a representative macrolide, and its derivatives have been found to show excellent anti-diffuse panbronchiolitis activity, and they now receive clinical attention beyond their original use as antibiotics. Moreover, the use of ivermectin, which was initially used as an antinematode agent for animals in 1981, procedures for exterminating onchocerciasis has been undertaken on a large scale. Consequently, in 1999 34 million people in an endemic area centered in Africa were saved from this disease with only a single annual administration. Thus, application of macrolides for clinical use has been a surprising development. [Pg.647]

S. antimycoticus Antinematodal activity Antineoplastic Antineoplastic activity Antineoplastic agent... [Pg.64]

Phytoalexins can be elicited in plants by a variety of agents, including viruses, microorganisms and nematodes [292, 293]. When resistant plants are infected by nematodes, phytoalexins with antinematodal activity can be produced [294]. Some coumestans have been implicated in the resistance of plants to nematodes. For example, when the roots of the resistant lima bean (Phaseolus lunatus) were inoculated with Pratylensus scribneri, coumestrol (181) accumulated at the site of nematode attack. In vitro, coumestrol (5 ig/ml) inhibited the motility of the nematode [294]. Correlative evidence for a functional role of related compounds in resistance towards nematodes has been obtained [295-297]. In particular, nematode attack on the roots elicits the transcription of genes encoding several enzymes of the shikimate pathway that leads to phytoalexin production. Induction of enzyme activity results from transcriptional activation of the genes leading to increased levels of translatable mRNA [298]. [Pg.472]


See other pages where Antinematodal agents is mentioned: [Pg.431]    [Pg.432]    [Pg.516]    [Pg.414]    [Pg.516]    [Pg.119]    [Pg.4]    [Pg.430]    [Pg.432]    [Pg.456]    [Pg.431]    [Pg.432]    [Pg.516]    [Pg.414]    [Pg.516]    [Pg.119]    [Pg.4]    [Pg.430]    [Pg.432]    [Pg.456]    [Pg.579]    [Pg.331]    [Pg.433]   
See also in sourсe #XX -- [ Pg.407 , Pg.435 , Pg.465 ]

See also in sourсe #XX -- [ Pg.2 , Pg.119 ]

See also in sourсe #XX -- [ Pg.26 , Pg.456 ]

See also in sourсe #XX -- [ Pg.456 ]




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