Antimicrobial susceptibility, trends

Providing descriptive data on the extent and temporal trends of antimicrobial susceptibility in Salmonella and other enteric organisms from human and animal populations. 

JONES RN (1992), Recent trends in the college of American pathologists proficiency results for antimicrobial susceptibility testing preparing for CLIA 88. Clin Microbiol Newsletter, 14,33-37. 

Over the last six decades, however, increased use of antimicrobial drugs, not only in human medicine, but in other areas, such as veterinary medicine, agriculture, and fish farming, has had an enormous impact on the microbial society. Nearly everywhere, the numbers of susceptible strains have reduced and resistant strains or variants have increased in numbers. It has been repeatedly reported that the susceptibility profile of bacteria in any human compartment, such as the skin, intestine, and respiratory tract, is very different from what it was in the pre-antibiotic era, and even 15 years ago. The same trend is reported from hospitals and homes. Multidrug resistance, that is resistance to several antimicrobial drugs, is commonly found in bacteria that cause infections as well as in commensal organisms. 

Pfaller MA, Diekema DJ, Jones RN, et al. Trends in antifungal susceptibility of Candida spp. isolated from pediatric and adult patients with bloodstream infection SENTRY Antimicrobial Surveillance Program, 1997-2000. J Clin Microbiol 2002 40 852-856. 

---