Antihelmintic drugs

Other examples of enantioseparations include the separation of the antihelmintic drug, prazinquatel [35], which used a 4-column SMB system composed of columns of 12.5 mm i.d. packed with CTA and with methanol as the eluent. Ikeda and Murata separated the enantiomers of (3-blockers [36]. 

Thiabendazole is an antihelmintic drug with a broad spectrum of action. Although the details of its mechanism of action are not conclusively known, it seems likely that its action is mediated by the inhibition of a specific enzyme of helminthes—fumarate reductase. Thiabendazole is active with respect to most nematode infections, including... 

Martin, R.J. (1 997) Modes of action of antihelmintic drugs. Veterinary journal 154, 11-34. 

Uses Diphenylamine is a colorless, monoclinic leaflet substance. It is used in the manufacture of a variety of substances, (e.g., dyestuffs and their intermediates pesticides, antihelmintic drugs, as a reagents in analytical chemistry laboratories). 

Which antihelmintic drug uncouples parasitic oxidative phosphorylation ... 

This fungicide and vermifuge agent is widely used in medical and veterinary practices as an antihelmintic drug. It induced contact dermatitis in two workers at an animal-feed production factory. 

Styrene epoxide is a valuable building block and is used in the production of the antihelmintic drug Levamisole. The styrene epoxide for the synthesis of drugs must be enantiopure. There are some chemical asymmetric synthetic routes but the yields are only in the range 45-50%. 

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