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Antihelminthic agents

The answer is a. (Hardman, pp 1020-1022.) Praziquantel is a broad-spectrum antihelminthic agent. It appears to kill the adult schistosome by... [Pg.81]

Helminthic infections are uncommon in developed nations. Antihelminthic agents are listed in Table 7.14. [Pg.118]

Crews and co-workers ° employed a 2-lithiooxazole in a key step of their synthetic strategy to prepare bengazole A 904, an antihelminthic agent isolated from marine sponges. Lithiation of 901 at —50°C followed by addition of 5-oxazolecarboxaldehyde 902 gave the bis-oxazolyl methanol 903 (Scheme 1.241). Acylation of 903 with myristoyl chloride and deprotection completed the synthesis of 904. [Pg.195]

Bengazoles contain a carbohydrate like polyol side chain together with a fatty acid ester. Both 1190a and 1190b are potent antihelminthic agents. [Pg.260]

Mebendazole An antihelminthic agent that blocks glucose uptake by parasitic round-worms. [Pg.1155]

Niclosamide An antihelminthic agent that interferes with carbohydrate metabolism. [Pg.1160]

The intramolecular esters, the lactones, may be mentioned here. The antihelminthic agent santonin, for example, belongs to this class. A well known lactone is coumarin, the odour of which resembles dried woodruff and which is found in numerous essential oils, also as derivatives. SuND and Saccabdi [273] have succeeded in separating 5 cou-marins on silica gel G layers, using petroleum ether (50—75° C)-ethyl acetate (67 + 33) or n-hexane-ethyl acetate (72 + 29). The sequence found was coumarin, 6-methylcoumarm, dihydrocoumarin, 3-methylcoumarin, 3-ethylcoumarin. [Pg.215]

Pipe razine is an antihelminthic agent (a drug used in the treatment of intestinal worms) that has molecular formula C4H10N2. The proton NMR spectrum of piperazine exhibits two signals. When dissolved in D2O, one of these signals vanishes over time. Propose a structure for piperazine. [Pg.1137]

A variety of structurally diverse compounds is used to eradicate or at least reduce the numbers of helminthic parasites in the intestinal tract or tissues of the body. The search for antihelminthics has been somewhat less systematic than for other microbial pathogens. Most of these agents were discovered by traditional screening programs their mechanisms of action at a molecular level are frequently unknown. [Pg.588]

Medicinally, copper sulfate is used as an emetic. It has also been used as an antihelminthic (antiparasitic agent) based on its astringent and caustic actions. [Pg.665]

Apart from their antibacterial action the nitrofurans have been tested as antiprotozoic, antihelminthic, antihypertensive and antineoplastic agents . The trials for these indications, however, are still in their neophyte stages, and it remains the task of future researchers to determine the importance of these additional indications for the nitrofurans. [Pg.368]

Uses bactericide antihelmintic algicide proposed as agricultural fungicide food additive in feed and drinking water for food-producing animals permitted in food for human consumption deodorant in germicide pharmaceuticals, antibacterial agent in soaps, cosmetics, veterinary antiseptic and antihelminthic products, industrial cleansers, etc. PA. PL A... [Pg.1198]


See other pages where Antihelminthic agents is mentioned: [Pg.227]    [Pg.137]    [Pg.117]    [Pg.331]    [Pg.250]    [Pg.223]    [Pg.43]    [Pg.482]    [Pg.267]    [Pg.274]    [Pg.227]    [Pg.137]    [Pg.117]    [Pg.331]    [Pg.250]    [Pg.223]    [Pg.43]    [Pg.482]    [Pg.267]    [Pg.274]    [Pg.1069]    [Pg.77]    [Pg.305]    [Pg.279]    [Pg.155]    [Pg.201]    [Pg.77]    [Pg.623]    [Pg.213]   
See also in sourсe #XX -- [ Pg.195 , Pg.260 ]




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