Myristoyl chloride

Figure 2. NMR spectra of PPO acylated with propionyl chloride (Sample No. 8, Table III) (IV), PPO acylated with myristoyl chloride (Sample No. 11, Table III) (V), and PPO acylated with -toluoyl chloride (Sample No. 14, Table III) (VI). (Reproduced with permission from ref. 17. Copyright 1987 Wiley.)...

The increase in the length of the side chain results normally in an internal plasticization effect caused by a lower polarity of the main chain and an increase in the configurational entropy. Both effects result in a lower activation energy of segmental motion and consequently a lower glass transition temperature. The modification of PPO with myristoyl chloride offers the best example. No side chain crystallization was detected by DSC for these polymers. 

Isopropyl myristate may be prepared either by the esterification of myristic acid with propan-2-ol or by the reaction of myristoyl chloride and propan-2-ol with the aid of a suitable dehydrochlorinating agent. A high-purity material is also commercially available, produced by enzymatic esterification at low temperature. 

The two Schotten-Baumann methods of preparing diacyl peroxides suffer from the formation of difficult emulsions in the alkaline medium and loss in yield due to hydrolysis of the acid chloride. Silbert and Swern developed an improved method involving acylation of 50-65% hydrogen peroxide with the acid chloride in ethei pyridine solution and obtained highly pure diacyl peroxides in nearly quantitative yield. For example, a solution of myristoyl chloride in ether is cooled to 0°. hydrogen... 

Crews and co-workers ° employed a 2-lithiooxazole in a key step of their synthetic strategy to prepare bengazole A 904, an antihelminthic agent isolated from marine sponges. Lithiation of 901 at —50°C followed by addition of 5-oxazolecarboxaldehyde 902 gave the bis-oxazolyl methanol 903 (Scheme 1.241). Acylation of 903 with myristoyl chloride and deprotection completed the synthesis of 904. 

Synonyms Gelatins, hydrolysates, myristoyl derivs. Myristoyl hydrolyzed animal protein Proteins, hydrolysates, reaction prods, with myristoyl chloride... 

See Potassium abietoyl hydrolyzed collagen Proteins, hydrolysates, reaction proeds. with myristoyl chloride, compds. with sodium. See Sodium myristoyl hydrolyzed collagen Proteins, hydrolysates, zinc salts. See Zinc hydrolyzed collagen Proteins, milk. See Casein Proteins, milk, hydrolysate. See Hydrolyzed milk protein... 

X = 6-16 6-Ocanyl chloride 10-Lauryl chloride 12-Myristoyl chloride 16-Stearoyl chloride... 

Ag-perchlorate dissolved in gently warmed nitromethane, Ga-sulfate as drying agent added, shaken and allowed to stand for a short time, glycerol 1-trityl ether 2,3-bis-(4-nitrobenzoate) added, allowed to stand briefly, myristoyl chloride added, after a few min. dry pyridine added drop wise until the color disappears glycerol 1-myristate 2,3-bis-(4-nitrobenzoate). Y 85%. F. e. s. H. Bredereck, A. Wagner, and D. Geissel, B. 9A, 812 (1961). 

Methylpropenoic acid 6733 Myristoyl chloride 9799 Nickel tetracarbonyl ... 

Synthesis of these types of material is usually achieved by esterification reactions of the 3-hydroxy group, often using a suitable acyl chloride (e.g. propionoyl chloride or myristoyl chloride) [41] this is illustrated in Scheme 1. 

Morpholinoisobutene MPTP Mucic acid Muscone Musk ketone Mustard gas Mycotoxin T2 Myricyl alcohol Myristic acid Myristo nitrile Myristoyl chloride Myrtenal... 

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