Antiepileptics analgesic activity

Gabepentin is an antiepileptic drug that has analgesic activity in neuropathic pain states from varying origins. Two recent randomised controlled trials of gabapentin in... 

A variety of drugs with antiepileptic, antispastic, or antidepressant activity are used to manage cranial neuralgias. These compounds are usually more useful than agents with general analgesic properties. 

Antiepileptic, psychiatric drug Lipid regulator (active metabolite) Metabolite of nicotine Antineoplastic Analgesic/antiinflammatory Analgesic/antiinflammatory Psychiatric drug (Prozac)... 

This is also identified as Chotoko in Japanese traditional medicine. It is composed of several Uncaria spp. including U. rhynchophylla, U. macrophylla, U. sinensis, and U. sessilifructus however, U. rhynchophylla is a major component. Gou-teng is commonly used for its sedative, antispasmodic, analgesic, anticonvulsive, hypertensive, antiepileptic, and antiviral properties [12]. The cmde drug is used to relieve headaches and dizziness caused by hypertension and infantile nervous disorders. Recent studies have evaluated that the active ingredients of Gou-teng are the alkaloids of U. rhynchophylla [12]. 

Only in the pharmaceutical area, there are more than 3,000 pharmaceutically active compounds (analgesics, anti-inilanunatory drags, antibiotics and antihistamines, p-blockers, lipid regulators, contraceptives, antidiabetics, antipsychotics, estrogens, antidepressants, anticonvulsionants, antiepileptics, stimulants, impotence drugs, etc.) that are used in human medicine. The main part of these pharmaceuticals is excreted in urine and feces and attains the aquatic environment water via wastewater and the effects of all these products alone or in combination are still not well known. In association with the pharmaceuticals, personal care products are normally smdied and the acronym PPCP was coined and adopted by many authors. ... 

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