Antibody 38C2-Catalyzed Retro-aldol Reactions and their Application to Kinetic Resolution

Antibody 38C2-Catalyzed Retro-aldol Reactions and their Application to Kinetic Resolution 

Enantioselective refro-aldol reaction (Kinetic resolution) rAIA 

Stereochemistry of antibody 38C2-catalyzed aldol reactions and kinetic resolution. 

In the aldol reactions to form secondary aldols the equilibrium constants favor the aldol product. For example, the aldol reaction of acetone with benzaldehyde has an equilibrium constant of 12 [17]. Aqueous solu- 

In the aldol reaction of acetone and acetophenone, the equilibrium constant is 0.002 [18]. A 1 mM solution of acetophenone would require the 

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