Antibodies soluble liver protein

Antibodies against soluble liver protein (SLAti P)... 

These antibodies, detected by M.R Manns et al. in 1987, are targeted against soluble cytoplasmatic liver protein as the target protein (SLA). (128) They are likely to be the antibodies described earlier by P.A. Berg (1981), which are directed against a liver-pancreas antigen (LP). Anti-SLA-positive patients are always anti-LP-positive as well. They are neither species-specific nor organ-specific, but characteristic of the existence of an im-... 

Rutin, quercetin 3-rutinoside, i.e., 3-rhamnoglucoside, has been reported to suppress glycation,609 but it is only sparingly soluble in water. Nagasawa el al.6W have therefore examined the water-soluble 4G-a-D-glucopyranosyl derivative (G-rutin), obtained from a sugar factory. Streptozotocin-treated rats were fed for 4 weeks on a 20% casein diet, when they showed an increase in fructosyllysine obtained on hydrolysis of their protein however, when their diet had been supplemented with 0.2% G-rutin, the increase was reduced by 20% for kidney protein. Supplementation reduced AGE accumulation, as measured with an anti-AGE monoclonal antibody, in the serum and kidney proteins to the level of the control rats. Supplementation inhibited aldose reductase activity in the kidney, but not in the liver. 

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