Aneurysms treatment

Kanaan, Y., Kaneshiro, D., Fraser, K., Wang, D. Lanzino, G. (2005) Evolution of endovascular therapy for aneurysm treatment. Neurosurgical Focus, 18, E2. 

Ortega, J., Maitland, D., Wilson, T., Tsai, W., Savas, O. Saloner, D. (2007) Vascular dynamics of a shape memory polymer foam aneurysm treatment technique. Annals of Biomedical Engineering, 35, 1870-1884. 

In a laser-activated medical device based on SMPU the indirect acmation of SME was induced by irradiation with IR-light [98, 99], Although the required energy is quite high, the principle could be extended to laser activated shape-memory vascular stents and SMP foams for aneurysm treatment [100, 101] both requiring a light diffuser for the uniform application of light [102]. 

Maitland et al. followed on this work with laser-activated foams for embolic aneurysm treatments [57]. In this study, the Tg of the foam was lowered to 45 °C and tested in an in vitro setup using 21 °C water, which is a 15°C shift in the Metcalfe conditions. Through proper laser power and absorption tuning, the foam devices were fully deployed under arterial flow conditions. In a parallel study, simulations were used to evaluate the performance of the device during deployment and after implantation [56]. Changes in blood flow patterns into the aneurysm, increases in hemodynamic stresses, and potential of thermal damage due to laser heating were all assessed. 

Neurovascular stents might help to repair the aneurysm bearing vessel segment with long lasting results, reflecting a more causative treatment than selective aneurysm occlusion Despite all the tremendous developments in techniques to treat aneurysms, treatment of the SAH itself and the sequelae is still less than desired and further research is urgently necessary to solve the problem of delayed ischemia... 

Neurointerventional methods concerning aneurysm treatment are broadly classified as deconstructive or... 

Weber W, Henkes H, Kuhne D (2000) Stent implantation into the basilar artery for supporting endovascular aneurysm treatment. Nervenarzt 71 843-848... 

Debrun G, Fox A, Drake C (1981) Giant unclippable aneurysms treatment with detachable balloons. AJNR Am J Neuroradiol 2 167-173... 

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