Analyte confirmation

Gas chromatography (GC) is used to analyze the sample extracts. Two detector systems are used, one for quantitation and the other for analyte confirmation and quantitation. 

GC was used to analyze the sample extracts. Three detection systems were used, two for quantitation and one for analyte confirmation. 

Reaction kinetics is concerned with rates of chemical transformations and thus experimental measurements must be of parameters which can be accurately related to changes in extent of a defined and characterized rate process, or set of rate processes. Yield-time data can only be significant if the stoichiometry of the reaction of interest is established, including analytical confirmation of the identities of the products, as well as any possible reaction intermediates. 

One well near Houserville drilled and cased to a depth of 200 feet in August of 1981 contained 22 ppt of marker compound (analytically confirmed). The continued presence of the compound in this well was not confirmed with additional sampling. 

Calculate concentration of each individual analyte confirmed present report results... 

Many organic pollutants in water can be analyzed with LC techniques at trace levels. From the different LC methods discussed in this entry, several remarks can be made 1) For routine water monitoring, LC/DAD is the most common detection device used to analyze polar, thermolabile, and non-volatile compounds due to its robustness, high sample throughput, and the possibility of obtaining a UV spectrum that can be used for analyte confirmation 2) LC/FD and ECD are more selective and sensitive than DAD and are especially useful for the monitoring of PAHs, carbamates, and phenols 3) LC/ MS with API sources and different combinations of mass analyzers have become highly robust techniques and the preferred option for the identification, confirmation, and... 

Avila, M., Zougagh, M., Escarpa, A., and Rios, A. (2009) Integrated microfluidic approach for simultaneous sample screening and analyte confirmation application to the detection of frauds in vanilla samples. Electrophoresis, 30, 3413-3418. 

Target compound analysis using high mass resolution, for example, for PCDD/ PCDFs, pesticides, POPs or pharmaceutical residues are typically performed by monitoring the compound-specific accurate mass ions at the expected retention time for each analyte. High resolution GC-MS target compound applications benefit from a unique technical feature referred to as the lock-mass technique for performing MID analyses. The lock mass technique provides ease of use, combined with a maximum quantitative precision and certainty in analyte confirmation. 

Sulfur mustard (SM) is unique among chemical warfare agents because of the large number of reports of its effects in man. The majority of these reports are of its effects after release on the battle field, and give a description of the types of effect and their time course from exposure to resolution of the injury. However, SM is also one of the few chemicals that have been the subject of tests on humans to determine how toxic they are in terms of the doses or dosages that produce toxic effects. Unlike reports of accidental or battlefield exposures, these trials were carried out in chambers under controlled, or at least carefully recorded, conditions, usually with analytical confirmation of chamber concentrations. Many of the reports of these trials, which were elassified at the time they were produced, have now been released into the public record and are available for scientific review. This chapter reviews those reports that are now available to the general public in addition to the work already published. Volunteer trials were carried out in the USA, UK, India and Australia. The reports of these trials that have been released to the public record are held by the Defense Technical Information Service... 

These figures must be interpreted with some caution. The authors comment on differences in the vesicating potency of different batches of SM, probably due to differences in the purity of the agent, which was not analytically confirmed. 

Modern methods of experimentation would require the purity of the SM to be specified and the concentrations in chambers to be analytically confirmed. In most of the chamber trials carried out in WWII these criteria were fulfilled, although the methods used were not always described, or referenced, in each report. However, good details of the concentrations achieved in the chambers are given within the individual experimental reports from the USA. In addition, the performance of the analytical methods in common use by each nation at the time that these studies were conducted are summarised in Porton Memorandum 19 and NRLR P-2208. The two methods that were in routine use were the iodoplatinate method and the bromine method. The performance of these methods in detecting... 

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