Amyloidosis primary systemic

Creutzfeldt-Jakob disease (CJD) Alzheimer s disease (AD) Hemodialysis-related amyloidosis Primary systemic amyloidosis Secondary systemic amyloidosis Familial amyloid polyneuropathy I Familial amyloid polyneuropathy III Cerebral amyloid angiopathy Finnish hereditary systemic amyloidosis Type II diabetes Injection-localized amyloidosis Medullary thyroid carcinoma Atrial amyloidosis... 

AL (fight chain) amyloidosis (primary systemic amyloidosis) Monoclonal immunoglobulin fight chains Systemic... 

Rajkumar, S. V., Gertz, M. A. and Kyle, R. A. Prognosis of patients with primary systemic amyloidosis who present with dominant neuropathy. Am. J. Med. 104 232-237, 1998. 

Alzheimer s Disease Spongiform encephalopathies Primary systemic amyloidosis Secondary systemic amyloidosis Familial amyloidotic polyneuropathy I Senile systemic amyloidosis Hereditary cerebral amyloid angiopathy Haemodialysis-related amyloidosis Familial amyloidotic polyneuropahy II Finnish hereditary amyloidosis Type n diabetes... 

Serra, L., Poppi, M.C., Criscuolo, M., Zandomeneghi, R. Primary systemic amyloidosis with giant hepatomegaly and portal hypertension a case report and a review of the literature. Ital. J. Gastroenterol. 1993 25 435-438... 

Kyle RA, Greipp PR. Primary systemic amyloidosis comparison of melphalan and prednisone versus placebo. Blood 1978 52 818-27. 

Kyle RA, Gertz MA. Primary systemic amyloidosis clinical and laboratory features in 474 cases. Semin Hematol 1995 32(l) 45-59. 

Hoyer RJ, Leung N, Witzig TE, et al. Treatment of diuretic refractory pleural effusions with bevacizumab in four patients with primary systemic amyloidosis. Am J Hematol 2007 82(5) 409 13. 

Berk JL, Keane J, Seldin DC, et al. Persistent pleiual effusions in primary systemic amyloidosis etiology and prognosis. Chest 2003 124(3) %9-977. 

Berk JL, Wiesman JF, Skinner M, et al. Diaphragm paralysis in primary systemic amyloidosis. Amyloid 2005 12(3) 193-196. 

Nephrotic syndrome is characterized by proteinuria greater than 3.5 g/day per 1.73 m, hypoproteinemia, edema, and hyperlipidemia. A hypercoagulable state may also be present in some patients. The syndrome may be the result of primary diseases of the glomerulus, or be associated with systemic diseases such as diabetes mellitus, lupus, amyloidosis, and preeclampsia. Hypoproteinemia, especially hypoal-buminemia, results from increased urinary loss of albumin and an increased rate of catabolism of filtered albumin by proximal tubular cells. The compensatory increase in hepatic synthesis of albumin is insufficient to replenish the protein loss, probably because of malnutrition. 

A condition in which there is extensive protein loss in the urint due to increased glomerular permeability. The glomerula disorder may be a primary condition (e.g. some types o glomerulonephritis) or secondary to other conditions, such a amyloidosis, diabetes mellitus and systemic lupus erythematosu The resultant hypoalbuminaemia causes oedema. 

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