Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Amyloid beta monomers

Sharoar MG, Thapa A, Shahnawaz M, Ramasamy VS, Woo ER, Shin SY et al (2012) Keampferol-3-O-rhamnoside abrogates amyloid beta toxicity by modulating monomers and remodeling oligomers and fibrils to non-toxic aggregates. J Biomed Sci 19 104... [Pg.534]

Bernstein, S. L. Wyttenbach, T. Baumketner, A. Shea, J. E. Bitan, G. TYplow, D. B. Bowers, M. T. Amyloid beta-protein Monomer structure and early aggregation states of Abeta42 and itsPprol9 alloform. J. Am. Chem. Soc. 2005, 127, 2075-2084. [Pg.721]

Alzheimer s Disease. Figure 1 A(3 monomers can self-associate to form dimers, trimers and higher oligomers. Globular structures of synthetic A(342 are known as A(3-derived diffusible ligands (ADDLs) (3-12-mers of A(3). These structures are similar to the smallest protofibrils and represent the earliest macromolecular assembly of synthetic A(3. The characteristic amyloid fiber exhibits a high beta-sheet content and is derived in vitro by a nucleation-dependent self-association and an associated conformational transition from random to beta-sheet conformation of the A(3 molecule. Intermediate protofibrils in turn self-associate to form mature fibers. [Pg.66]

Nichols MR, Moss MA, Reed DK, Lin WL, Mukhopadhyay R, Hoh JH, Rosenberry TL (2002) Growth of beta-amyloid(l-40) protofibrils by monomer elongation and lateral association. Characterization of distinct products by light scattering and atomic force microscopy. Biochemistry 41 6115-6127 Niewold TA, Murphy CL, Hulskamp-Koch CA, Tooten PC, Gruys E (1999) Casein related amyloid, characterization of a new and unique amyloid protein isolated from bovine corpora amylacea. Amyloid 6 244-249... [Pg.71]

It has been found in recent studies that water plays a major role in the process of beta-amyloid aggregation [15] in the early and late stages of fibril formation and interactions with water greatly affect the folding energy landscapes of beta-amyloid monomers [15,16]. [Pg.110]

Yu X, Zheng J. Cholesterol promotes the Interaction of Alzheimer beta-amyloid monomer with lipid bilayer. / Mol Biol. 2012 421(4-5) 561-571. [Pg.274]


See other pages where Amyloid beta monomers is mentioned: [Pg.91]    [Pg.91]    [Pg.112]    [Pg.64]   
See also in sourсe #XX -- [ Pg.91 ]




SEARCH



Amyloid

© 2024 chempedia.info