Supramolecular amperometric sensors

Electrocatalytic groups such as porphyrins and phthalocyanines that act as supramolecular hosts for different metals and mimic the active sites of various proteins are commonly used in amperometric sensors [66,67]. A biomimetic sensor based on an artificial enzyme or synzyme has been demonstrated [68]. The artificial enzyme used in this study was a synthetic polymer (quaternised polyethyleneimine containing 10% primary amines) which decarboxylated oxaloacetate. The product carbon dioxide was detected potentiometrically via a gas membrane electrode. 

There is considerable interest in electrochemical sensing within the field of supramolecular chemistry, and the topic has been identified as an important applicable area of host-guest chemistry. This review covers developments in the area of supramolecular voltammetiic/ amperometric sensors, where current is measured as a function of applied potential. The area of supramolecular potentiometric sensors (e.g., ion-selective electrodes) is not covered here, and the reader is referred to a general review on electrochemical sensors that covers this topic. ... 

Damos FS, Luz RC, Tanaka AA, Kubota LT (2010) Dissolved oxygen amperometric sensor based on layer-by-layer assembly using host-guest supramolecular interactions. Anal Chim Acta 664(2) 144-150... 

Ozoemena [125] performed the anodic oxidation and amperometric sensing of hydrazine using a glassy carbon electrode modified with a cobalt(ll) phthalocya-nine-cobalt(n) tetraphenylporphyrin (CoPc-(CoTPP)4) supramolecular complex. This amperometric sensor displayed excellent characteristics for the determination of hydrazine in 0.2 M NaOH at low overpotential (+100 mV vs. Ag/AgCl), with very fast amperometric response time (1 s), linear range of 10-230 pmol LT, limit of detection of 1 pmol L and sensitivity of 0.0157 pA L pmol . ... 

F.-C. Gong, X.-B. Zhang, C.-C. Guo, G.-L. Shen, and R.-Q. Yu, Amperometric metronidazole sensor based on the supramolecular recognition by metallopor-phyrin incorporated in carbon paste electrode, Sensors, 3 (2004) 91-100. 

Ozoemena KI (2006) Anodic oxidation and amperometric sensing of hydrazine at a glassy carbon electrode modified with cobalt (II) phthalocyanine-cobalt (II) tetraphenylporphyrin (CoPc-(CoTPP)4) supramolecular complex. Sensors 6 874—891... 

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