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2-Amino-1 -methyl-6-phenylimidazo -pyridine PhIP

Aoki, H. et al., Inhibitory effect of anthocyanin colors on mutagenicity induced by 2-amino-l-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), Foods Food Ingred. J. Jpn., 209, 240, 2004. [Pg.498]

Kobayashi, M., Hanaoka, T., et al. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) level in human hair as biomarkers for dietary grilled/stir-fried meat and fish intake. Mutat. Res. 588(2), 136-142, 2005. [Pg.636]

Strickland, P. T., Qian, Z., Friesen, M. D., Rothman, N., and Sinha, R. Metabolites of 2-amino-l-methyl-6-phenylimidazo(4,5,-b)pyridine (PhIP) in human urine after consumption of charbroiled or fried beef. Mutat. Res. 2002.163-173, 506-507. [Pg.636]

Figure 11.4. Structures of various heterocyclic amines. IQ is 2-amino-3-methylimidazo-quinoline. MelQx is 2-amino-3,8-dimethylLtnidazo-quinoxalme. 4,8-DiMelQx is 2-amino-3,4,8-trimethylimidazo-quinoxaline. PhIP is 2-amino-l-methyl-6-phenylimidazo-pyridine. These and other related compounds can be found in fried or broil beef, fish, and chicken, but can also be created by cooking mixtures of creatinine, amino acids, and glucose. Microwave cooking, or cooking in aluminum foil, reduces the formation of heterocyclic amines. (From Sugimura, 1997.)... Figure 11.4. Structures of various heterocyclic amines. IQ is 2-amino-3-methylimidazo-quinoline. MelQx is 2-amino-3,8-dimethylLtnidazo-quinoxalme. 4,8-DiMelQx is 2-amino-3,4,8-trimethylimidazo-quinoxaline. PhIP is 2-amino-l-methyl-6-phenylimidazo-pyridine. These and other related compounds can be found in fried or broil beef, fish, and chicken, but can also be created by cooking mixtures of creatinine, amino acids, and glucose. Microwave cooking, or cooking in aluminum foil, reduces the formation of heterocyclic amines. (From Sugimura, 1997.)...
Ito, N., Flasegawa, R., Sano, M., Tamano, S., Esumi, H., Takayama, S., and Sugimura, T. (1991). A new colon and mammary carcinogen in cooked food, 2-amino-l-methyl-6-phenylimidazo[4,5-p]pyridine (PhIP). Carcinogenesis 12,1503-1506. [Pg.919]

Shioya M., Wakabayashi K., Sato S., Nagao M. and Sugimura T. Formation of a mutagen, 2-amino-l-methyl-6-phenylimidazo[4,5-b]-pyridine (PhIP) in cooked beef by heating a mixture containing creatinine, phenylalanine and glucose. Mutation Research. 191,133. 1987... [Pg.40]

LOW-DOSE CARCINOGENICITY OF 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[5,6-B]PYRIDINE (PhIP) IN THE RAT COLON... [Pg.215]

Styczynski, P.B., Blackmon, R.C., Groopman, J.D., and Kensler, T.W. (1993) The direct glucuronidation of 2-amino-l-methyl-6-phenylimidazo[4,5-fe]pyridine (PhIP) by human and rabbit liver microsomes. Chem. Res. Toxicol.,... [Pg.177]

Yadollahi-Farsani, M., Gooderham, N.J., Davies, D.S., and Boobis, A.R. (1996) Mutational spectra of the dietary carcinogen 2-amino-l-methyl-6-phenylimidazo[4,5-k]pyridine (PhIP) at the Chinese hamsters hprt locus. Carcinogenesis, 17, 617-624. [Pg.179]

Burnouf, D., Miturski, R., Nagao, M., Nakagama, H., Nothisen, M., Wagner, J., and Fuchs, R.P. (2001) Early detection of 2-amino-1-methyl-6-phenylimidazo[4,5-fc]pyridine (PhIP)-... [Pg.180]

Benzo[a]pyrene and other polycyclic hydrocarbons 2-Amino-1 -methyl-6-phenylimidazo-[4,5-i)]pyridine (PhIP)... [Pg.384]

Manabe S, Suzuki H, Wada 0, Ueki A. Detection of the carcinogen 2-amino-l -methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in beer and wine. Carcinogenesis 1993 14 899-901. [Pg.145]

Andreassen, A., Vikse, R., Mikalsen, A., Adamovic, T., Steffensen, I.L., Hjerthohn, H., Levan, G., and Alexander, J. (2006) 2-Amino-l-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induces genetic changes in murine intestinal tumours and cells with ApcMin mutation. Mutat. Res. 604, 60-70. [Pg.287]

Hegstad, S., Ingebrigtsen, K., Reistad, R., Paulsen, J. E., and Alexander, J. 2000a. Incorporation of the food mutagen 2-amino-l-methyl-6-phenylimidazo[4, 5-b]pyridine (PhIP) into hair of mice. Biomarkers 5 24-32. [Pg.171]

Prabhu, S., Lee, M. J., Hu, W. Y., Winnik, B., Yang, I., Buckley, B., and Hong, J. Y. 2001. Determination of 2-amino-l-methyl-6-phenylimidazo(4,5-B)pyridine (PhIP) and its metabolite 2-hydroxyamino-PhIP by liquid chromatography/electrospray ionization-ion trap mass-spectrometry. AnaZ. Biochem. 298 306-313. [Pg.174]

Figure 13.8 Mutagenic and carcinogenic heterocyclic amines (a) IQ (2-amino-3-methylimidazo[4,5-/ quinoline), (b) IQx (2-amino-3-methylimidazo[4,5-/ quinoxaline), (c) PhIP, (2-amino-l-methyl-6-phenylimidazo[4,5- ] pyridine), (d) 1,5,6-TMIP (2-amino-l,5,6-trimethylimidazo[4,5-6] p5ridine). Figure 13.8 Mutagenic and carcinogenic heterocyclic amines (a) IQ (2-amino-3-methylimidazo[4,5-/ quinoline), (b) IQx (2-amino-3-methylimidazo[4,5-/ quinoxaline), (c) PhIP, (2-amino-l-methyl-6-phenylimidazo[4,5- ] pyridine), (d) 1,5,6-TMIP (2-amino-l,5,6-trimethylimidazo[4,5-6] p5ridine).
Amino-2-methylanthraquinone 2-Amino-3-methylimidazo[4,5-/]quinoline (see IQ) 2-Amino-6-methyldipyrido[l,2-a 3, 2 -fil]imidazole (see Glu-P-1) 2-Amino-l-methyl-6-phenylimidazo[4,5-6]pyridine (see PhIP)... [Pg.532]

See other pages where 2-Amino-1 -methyl-6-phenylimidazo -pyridine PhIP is mentioned: [Pg.389]    [Pg.396]    [Pg.823]    [Pg.400]    [Pg.575]    [Pg.441]    [Pg.442]    [Pg.19]    [Pg.302]    [Pg.207]    [Pg.159]    [Pg.315]    [Pg.71]    [Pg.545]    [Pg.277]    [Pg.171]    [Pg.199]    [Pg.1812]    [Pg.908]    [Pg.911]    [Pg.103]    [Pg.132]    [Pg.384]   
See also in sourсe #XX -- [ Pg.537 ]



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1- Methyl pyridine

2- Phenylimidazo pyridine

2- [ amino pyridin

2-Amino-6-phenylimidazo pyridine

Phip

Pyridin methylation

Pyridine, 3-amino

Pyridines amino-, methylation

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