3- Amino-4-benzyloxy- -Hydrochlorid

L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophanyl-L-lysyl-L-threonyl-L-threonyl-L-cysteine 6-0-benzoyl-N-(benzyloxycarbonyl) methylamide 4,6-0-benzylidene-N-benzylidene-N-(benzyloxycarbonyl) methylamide N- (benzyloxy carbonyl) -N-(benzyloxycarbonyl)-, amide N-(benzyloxycarbonyl)-, hydrazide N-(benzyloxycarbonyl)-, methylamide N-(benzyloxycarbonyl)-, methyl ester N-(benzyloxycarbonyl)-L-alanyl-L-alanine methyl ester N-(benzyloxycarbonyl)-L-alanylglycine ethyl ester N-(benzyloxycarbonyl)glycyl-L-alanine methyl ester 3,4,6-tri-0-acetyl-2-amino-2-deoxy-N-(benzyloxycarbonyl)-, benzyl ester, hydrochloride... 

Benzyloxy-4-isopropyl(or 4-terf-butyl)-4-methyl-5(4//)-oxazolones 780 have been prepared from an A-benzyloxycarbonylamino acid 779 using l-(3-dimethyl-aminopropyl)-3-ethylcarbodiimide hydrochloride (EDAC HCl) as the cyclization agent (Scheme 7.237). Treatment of 780 with tetramethylfiuoroformamidinium hexafiuorophosphate (TFFH) has shown that they are possible intermediates in the fluorination of a-methyl-a-alkyl amino acids by TFFH. 

Die leichte Spaltbarkeit von 1,3-Oxazol-Derivaten macht diese zu geeigneten Ausgangs-materialien fur die Synthese von 2-Amino-a kanolen, wie die Herstellung von 3-Amino-4-benzyloxy-l, 2-butandiol-Hydrochlorid bus 4-(Benzyloxy-methyl)-5-hydroxymelhyl-2-tri-chlormethyl-4,5-dihydro-l,3-oxazol zeigt2 ... 

S, 5.S )-2-(2-Aminopropyl)-5-[(benzyloxycarbonyl)amino]-6-(indol-3-yl)-4-oxohexanoic Add Hydrochloride Salt (22, R1 = 3-methylindolyl R2=2-NH2Pr) and (2R/S,5S)-5-[(Benzyloxy-carbonyl)amino]-2-(2-guanidylpropyl)-6-(indol-3-yl)-4-oxohexanoic Add Hydrochloride Salt (22,... 

Amino-2-(3-amino-phenyl)- 889 2-(4-Amino-anilino)- 1001 2-(N1 -Amino-N2-aryl-thioureido)- 1002 2-(4-Amino-benzolsulfonylamino)- 885 2-Amino-5-benzyloxy-6-methoxy- 878 -Hydrochlorid... 

The reduction of 2- benzyl(methyl)amino]-l-[3-(benzyloxy)phenyl]ethanone was carried out with the same in situ rhodium/phosphane catalyst to give (S)-2-[benzyl(methyl)amino]-l-[3-(benzyl-oxy)phenyl]ethanol in 85 % ee44 (Table 6). This reaction constitutes the enantioselective step in a synthesis of (tf)-phenylephrine hydrochloride, another /1-receptor-stimulating agent having a chiral benzylic alcohol group44. 

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