4-Amino-4H -1,2,4-triazole

Amino-y-sym-tr iozole or 4-Amino-4H-. 1,2,4-triazole (Called in some papers, 4-Amino-4,l,2-triazole), HC=N-N. Hygr... 

Structures of guanazo- and pyroguanazoles, and reaction of dicyandiamide with 3-amino-5-substituted-4H- 1,2,4-triazoles)... 

Cyclopropan 1-Azido-l-dimethyl-amino- E17b, 1593 (OH - N3) Guanidin 4-Cyan-l-propyl- E4,1299 (OR - NH-C3H7) lH-Tetrazol 1-Butyl- E8d, 679 [HC(OR)3 + R-NH2/NaN3] 4H-1,2,4-Triazol... 

Methyl-2-(4H-1.2,4-triazol-4-yl-amino)- 877 2-Mcthyl-6-trifluormethansulfonyl- 870 2-Morpholino- 976, 983 2-(Morpholinodisulfano)- 998... 

P-(4H-1,2,4-triazol-4-yl)ketones 4H-1,2,4-Triazoles, 4-amino--, amination, vicarious with - 44, 336... 

Amino-l,2,4-triazole undergoes a cyclocondensation with 3-etlioxyacrolein (7) to form 1,2,4-triazolo[l,5-a]pyrimidine (3) or its [4,3-u] isomer (5), according to whether it reacts as IH or 4H tautomer 2 or 4. Moreover, the pyrimidines 3 and 5 can interconvert by a Dimroth rearrangement. Since the H NMR spectrum 30a does not enable a clear distinction to be made AMX systems for... 

Uber eine Relais-Synthese lassen sich aus 4-(a-Amino-benzy]idenamino)-4H-l,2,4-triazolcn mit Carbonsaureanhydriden oder Carbonsaure-chloriden in Dimethylformamid 2-substi-tuierte 1,3,4-Oxadiazole im Eintopfverfahren herstellen552,553. Diese Reaktion verlauft iiber Acyl-hydrazone von 1-Formyl-3-phenyl-l,2,4-triazol, dessen Pyrolyse ebenfalls gute Aus-beuten liefert552. Mit dieser Methode konnten einige 1,3,4-Oxadiazole in besseren Ausbeuten und groBerer Reinheit als nach anderen Verfahren synthetisiert werden. 

AminD-3,5-dioxo-1,2,4-triazoiidine oi Urazine, 4-amino-[iH-1,2,4-triazole-34 5 (2H.4H)-dione]. See 4-Aminourazole... 

An interesting Mossbauer study has been reported on the dinuclear SCO complex [Fe2 (PMAT)2](BF4)4-DMF (PMAT 4-amino-3,5-bis [(2-pyridylmethyl) amino]methyl -4H-1,2,4-triazole), where thermal ST occurs from [HS-HS] to the stable endproduct [HS-LS] [32]. The molecular structure and magnetic behavior of this complex was reported earlier by Brooker et al. [33, 34] (Fig. 8.15). At ca. 225 K, the complex undergoes a sharp half ST from the HS state, T2, to a state containing 50% HS and 50% LS, Af, isomers. The single-crystal structural analysis... 

Amino-5-hydrazino-3-mercapto-4H-s-triazale, or 4- Am i no- 5-h yd ra z i no-4H-1,2,4-tri azol e-3-fhione(Called in Beil 4-Amino-3-hydrazono-3-tbion-l,2,4-triazolidin) (Called 4-Amino-3-hydrazino-5-mercapto-1,2,4-triazole in Refs 3,4 5), H2N-HN C=N-N or H,N N C-NH-NH. 

A solution of 158.5 g of 2-chloro-2, 4 -difluoroacetophenone and 88.8 g of 4-amino-4H-l,2,4-triazole in 1,600 ml of cyanomethane was heated at reflux for 16 hours, cooled down, and filtered. The solid thus obtained was then washed with 500 ml of ethyl ether once to afford 2-(lH-l,2,4-triazol-l-yl)-2, 4 -difluoroacetophenone salt. 

Ainino-4-mcrcapto-3-methyl-l-phenyl- 660 5(3)-(4-Amino-5-mercapto-4H-1.2.4-triazol-3-yl)-... 

AHMT (4-amino-3-hydrazino-5-mercapto-4H-1,2,4-triazole) reacts on aldehydes in strongly alkaline media to form a colorless intermediate product. This product is oxidized by atmospheric oxygen to give a purple-colored dye. The resulting chromophore has four conjugated double bonds the molecular formula shown in Eq. (4) is one of... 

An improved synthesis of 5-substituted 4-amino-3-mercapto-(4H)-1,2,4-triazoles (105) has been reported which involves the reaction of thiocarbohydrazide with carboxylic acids at the melting temperature. The crude triazoles (105) then provided easy access to the 3,6-disubstituted l,2,4-triazolo[3,4-b][l,3,4]thiadiazoles (106) by reaction with carboxylic acids or their acid chlorides <97JHC1255>. 

Other fused 1,3,4-thiadiazoles have been prepared and include 4H-1,3,4-thiadiazolo[2,3-c]-l,2,4-triazin-4-ones (108) which were obtained by the reaction of 4-amino-4,5-dihydro-3-(methylthio)-l,2,4-triazin-5-ones (107) with benzoyl isothiocyanates and with methoxycarbonyl isothiocyanates. The corresponding five membered fused system (110) was prepared by reaction of the triazole (109) with benzoyl isothiocyanate <97JHC1351>. ... 

Kauhaluoma and Samanta used miinchnone as the key intermediate to obtain a triazole core (Scheme 9.41). Starting with Ameba resin 351, 3.84 equiv of amino acid ester 352 and 25 equiv of NaBHaCN were employed for the reductive alkylation in 1% acetic acid in DMF at room temperature for 12 h. Resin 353 was treated with 10 equiv of carboxylic acid chloride 354 in the presence of 12 equiv of A,A-diisopropylethylamine in DCM at room temperature for 12h to form amide 355, which was treated with 5% KOH in dioxane H20 (3 1) for 4h to give the corresponding carboxylic acid. Resin 356 was treated with 23.5 equiv of acetic acid anhydride, 3 equiv of DEAD (diethyl azodicarboxylate) 357, and 3 equiv of 4-phenyl-4/f-l,2,4-triazoline-3,5-dione 358 in DCM at room temperature for 5-10 h, giving the miinchnone intermediate 359, which reacted with compound 357 or 358 to form resin 360. Treatment of this with 30% TFA in DCM at room temperature for 1.5 h resulted in cleavage from the resin, producing 361. 

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