Qualitative organic analysis amines

Chapter 70 Qualitative Organic Analysis TABLE 6 Tertiary Amines... 

Emil Fischer and most students in qualitative organic analysis were familiar with the reactions of monofunctional isoqranates with alcohols, amines and aldehydes. Otto Bayer, who was manager of research of the LG. Farben-industrie Laboratories at Leverkusen extended these simple reactions to difunctional reactants and obtained a versatile family of pol30irethane fibers, foams, elastomers, plastics and coatings. 

Suitable reagents for derivatizing specific functional groups are summarized in Table 8.21. Many of the reactions and reagents are the familiar ones used in qualitative analysis for the characterization of organic compounds by physical means. Alcohols are converted to esters by reaction with an acid chloride in the presence of a base catalyst (e.g., pyridine, tertiary amine, etc). If the alcohol is to be recovered after the separation, then a derivative which is fairly easy to hydrolyze, such as p-nltrophenylcarbonate, is convenient. If the sample contains labile groups, phenylurethane derivatives can be prepared under very mild reaction conditions. Alcohols in aqueous solution can be derivatized with 3,5-dinitrobenzoyl chloride. 

Benzenesulfonyl chloride (66) is used in organic qualitative analysis for the separation of primary (67), secondary (68) and tertiary (69) amines by the Hinsberg method (Scheme 39). The alkaline reaction mixture is first filtered, which removes the precipitate of the... 

TLC analysis of agricultural products, foods, beverages, and plant constituents is described by Sherma in a review paper. In laboratories throughout the world, TLC is widely used for food analysis and qualitative control. Numerous applications of TLC have been reported in the area of food composition, involving determinations of compounds such as lipids, sugars, amines, vitamins, and organic acids such as amino acids and fatty acids. 

In sections II.A to II.D the main features of the amino group were examined from the point of view of organic qualitative and quantitative analysis. Section IV will deal with some of the structural problems posed by amines. It is convenient to bridge these two aspects of analysis with a brief examination of hydrogen bonding in the amino group, which has a deep influence on a wide range of physical and chemical properties used in the elucidation of molecular structure. The im- ... 

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