Amines n-propylamine

The triplet reaction of 2-nitrodibenzo[fc,primary amines (n-propylamine and benzylamine) was studied110 in polar and apolar solvents. In polar solvents, the irradiation results in the formation of two isomeric compounds, (alky-lamino)hydroxynitrodiphenyl ether andiV-(alkylamino)-2-nitrophenoxazine (equation 54). In apolar solvents, only the nitrophenoxazine is obtained. In polar solvents, the exciplex formed between the 2-n i trodi benzol h,e [ 1,4]dioxin triplet state and amines dissociates to the solvated radical ions, from which the diphenyl ether arises. 1-Nitrodibenzo[fr,e][l,4]dioxin is stable even on prolonged irradiation. 

Biogenic amines are usually detected by LC with a pre- or postcolumn derivatization with o-phthalaldehyde in the presence of mer-captoethanol, and fluorimetric detection of derivatives. A sample derivatization also has to be done to perform GC/MS analysis of grape juice or wine. Amines are distilled from the alkalized sample and trapped in an acidified solution. After concentration under vacuum, salts of ethylamine, dimethylamine, ethylamine, diethyl-amine, n-propylamine, isobutylamine, a-amylamine, isoamylamine, pyrrolidine, and 2-phenethylamine are derivatized with trifluoroacetic (TEA) anhydride. Their derivatives are extracted with ethyl ether. GC/MS is performed using a capillary fused silica PEG column with an oven temperature programmed for 8 min at 70 °C, l°C/min to 160°C, isotherm for 90min (Daudt and Ough, 1980). 

Hydrochloride niederer aliphatischer Amine (> n-Propylamin) lassen sich bei etwas erhohten Temp, glatt in Amnioalkansulfochlorid Hydrochloride iiberfuhren7. Beim Athyl-amin liegt die Ausbeute bei < 1% d.Th. 

B) Secondary amines, (i) Aromatic amines. Monomethyl and monoethylaniline, diphenylamine. (ii) Aliphatic and other amines. Diethyhmine, di-n-propylamine, di-isopropylamine. Also piperidine piperazine diethylene-diamine). 

Propylamine (pnmary amine) N Methylethylamine (secondary amine) Tnmethylamine (tertiary amine)... 

Ethyleneimine reacts with (p-tolylsulfonyl)acetylene to give only the (Z)-product 115 via trans addition (equation 91), while primary and secondary aliphatic amines afford ( )-products76. With nonterminal acetylenes such as l-(ethylsulfonyl)-l-propyne, the reactions of ethyleneimine, n-propylamine and f-butylamine give mixtures of ( )- and (Z)-adducts. The double conjugate addition of sodium sulfide, selenide and telluride to bis(l-propynyl)sulfone (116) produces heterocycles (117) as illustrated in equation 9277. 

Oxidative carbonylation generates a number of important compounds and materials such as ureas, carbamates, 2-oxazolidinones, and aromatic polycarbonates. The [CuX(IPr)] complexes 38-X (X = Cl, Br, I) were tested as catalysts for the oxidative carbonylation of amino alcohols by Xia and co-workers [43]. Complex 38-1 is the first catalyst to selectively prepare ureas, carbamates, and 2-oxazolidinones without any additives. The important findings were the identity of the counterion and that the presence of the NHC ligand influenced the conversions. 2-Oxazohdinones were formed from primary amino alcohols in 86-96% yield. Complex 38-1 also catalysed the oxidative carbonylation of primary amines to ureas and carbamates. n-Propylamine, n-butylamine, and t-butylamine were transformed into the... 

To synthesize new surfactants, having incorporated both structural elements, the known siloxanyl modified halogenated esters and ethers of dicyclopentadiene [5] were treated with different amines according to the reaction scheme. Triethylamine yielded quaternary ammonium salts directly. Alternatively, after reaction with diethylamine or morpholine, the isolated siloxanyl-modified tertiary amines were also converted to quaternary species. To obtain anionic surfactants, the halogenated precursors were initially reacted with n-propylamine. In subsequent reaction steps the secondary amines formed were converted with maleic anhydride into amides, and the remaining acid functions neutralized. Course and rate of each single reaction strongly depended on the structure of the initial ester or ether compound and the amine applied. The basicity of the latter played a less important role [6]. 

Figure 10 Separation of ABEI-DSC-derivatized n-octylamine (2) and n-propylamine (3) with ECL detection. Remaining ABEI (1) and ABEI DSC (not shown) are also detected. Conditions 20% methanol in 5 mM sodium borate separation buffer, pH 10.9 5-s injection at 25 kV, 1.0 X 10 6 for each labeled amine 25-kV separation potential 10-mm platinum wire electrode. (From Ref. 85, with permission.)...

Other clear-cut evidence that the dichotomy between primary and secondary amines cannot be due to differential steric compression in the tr-complexes formed in these reactions has been afforded by Nudelman and Cerdeira82 in their study of the reactions of o-and p- lluomn i Irobenzenes with two primary amines n- and iso-propylamine in... 

N-nitrosamines are a group of compounds characterized by a nitroso group (N=0) attached to the nitrogen of an aromatic or aliphatic secondary amine. N-nitrosodi-N-propylamine is a suspected reaction byproduct from the nitrosation of di-N-propylamine. Two pesticides are suspected to contain some form of nitrosamines. 

NCA polymerization by secondary amines may involve the amine or activated monomer mechanisms or both mechanisms simultaneously. Unhindered secondary amines such as dimethylamine and piperidine react like primary amines, and polymerization occurs by the amine mechanism. Polymerization by slightly hindered amines such as diethylamine, N-methylbenzylamine, and di-n-propylamine involves a combination of the amine and activated monomer mechanisms. More hindered secondary amines, such as di-n-isopropylamine and dicyclohexylamine, react almost exclusively via the activated monomer mechanism. 

Like the oxa method for naming ethers (Problem 14.61), the aza method is used for amines. Di-n-propylamine, CH3CH2CH2NHCH2CH2CH3, is 4-azaheptane and piperidine is azacyclohexane. The four H s of NH can be replaced to give a quaternary (4°) tetraalkyl (tetraaryl) ammonium... 

Aliphatic Amines Butylamine Cyclohexylamine Dibutylamine Diethylamine Diethylenetriamine Dilsopropylamine Dimethylamine Di-n-propylamine Ethylamine Ethylenediamine Hexamethyleneimine Methylamine Morpholine Propylamine... 

Figure 15. Open tubular liquid chromatography of amine-NBD derivatives using on-column fluorescence detection. Peaks correspond from left to right to ethylamine, n-propylamine, n-butylamine, cyclohexylamine, and n-hexylamine. Conditions 20-p.m X 8.3-m column with C-18 bonded phase 20% acetonitrile and 80% water (v/v) mobile phase at a linear velocity of 0.50 cm/s on-column injection of 5 nL. (Reproduced from reference 59. Copyright 1984 American Chemical Society.)...

Korenman et al. [45] studied the solvent-water partition coefficients Ksv/ of ethylamine, n-propylamine, and n-butylamine at 20°C. Based on the data for these amines with a short, linear alkyl chain, the contributions to the logarithm of the solvent-water partition coefficients were found to be constant among particular solvent classes. The contribution values are shown in Table 13.4.1. Accordingly, A log K0VI for CH2 is 0.50. 

The fluorescence of If is not quenched by primary amines and the formation of t-l-primary amine adducts have not been reported. Irradiation of t-1 or c-1 in n-propylamine solvent yields 1,4-dihydrophenanthrene, 70 (134). Deuterium labeling studies suggest the role of the amine is that of a base catalyst in the isomerization of the initially formed 4a,4b-dihydro-phenanthrene (eq. 24). 

A large family of other N-substituted homologues of 2,4-DMA were similarly prepared from the above ketone and sodium cyanoborohydride. Methyl-amine, ethylamine, propylamine, isopropylamine and hexylamine gave the corre-... 

The structure of MDA can be viewed as an aromatic ring (the 3,4-methylenedioxyphenyl ring) with a three carbon chain sticking out from it. The amine group is on the second of the three carbon atoms. The isomers, with the amine function moved to the first of these carbons atoms (a benzylamine) and with the amine function moved to the third (furthest out atom) of these carbon atoms (a (n)-propylamine), are known and both have been assayed. 

The (n)-propylamine counterpart (as if one were to move the amine function the other direction, from the beta-carbon to the gamma-carbon of the three carbon chain of the amphetamine molecule) is gamma-3,4-methylenedioxy-phenylpropylamine or 1 -amino-3-(3,4-methylenedioxyphenyl)propane, GAMMA. The hydrochloride salt has a mp of 204-205 °C. At oral levels of 200 milligrams there was some physical ill-at-ease, possible time distortion, and a feeling of being keenly aware of one s surroundings. The duration of effects was 4 hrs. 

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