Amago salmon

Nakamura M, Nagoya H, Hirai T (2002) Nonylphenol induces complete feminization of the gonad in genetically controlled all-male amago salmon. Fish Sci 68 1387-1389... 

The pharmacokinetics and tissue levels of nalidixic acid were determined after oral administration of a single dose of 40 mg drug/kg bw to cultured rainbow trout and amago salmon held at 15 C (181). The absorption rate of the drug was found to be nearly equal for the two species and was completed within 48 h. Nalidixic acid could be detected in all tissues of both species at as early as 0.5 h after dosing. 

In a study in which rainbow trout were administered oxolinic acid for 7 days at a dosage of 12 mg/kg bw/day, drug level in muscle tissue was 0.03 ppm at 10 days withdrawal (194). In amago salmon held at 15 C and given a single oral dose of 40 mg/kg bw, oxolinic acid concentrations of 0.02 ppm could still be detected in muscle tissue at day 30 after administration (195). In yellowtail held at 24.5 C and administered oxolinic acid at a dose of 50 mg/kg bw, concentrations of 0.09 ppm and 0.17 ppm were recorded in muscle and kidney tissues, respectively, at day 8 posttreatment (196). 

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