Inflammation Alzheimer’s disease

Moreover,bioactive lipids maybe considered dual messengers they modulate cell functions as messengers and they become part of the response of the nervous tissue to injury, broadly referred to as the inflammatory response. This response occurs in ischemia-reperfusion damage associated with stroke, various forms of neurotrauma, infectious diseases and neurodegenerative diseases such as Alzheimer s disease. Inflammation in the nervous system differs from that in other tissues. If the blood-brain barrier is broken, blood-borne inflammatory cells (e.g. polymorphonuclear leukocytes, monocytes, macrophages) invade the intercellular space and glial cells are activated, particularly microglia, which play a prominent role in the inflammatory response. These responses may... 

Casserly 1, Topol E (2004) Convergence of atherosclerosis and Alzheimer s disease inflammation, cholesterol, and misfolded proteins. Lancet 363 1139-1146... 

Str olimeyer R, Rogers J (2001) Molecular- and cellular- mediators of Alzheimer s disease inflammation. J Alzheimers Dis 3 131—157. 

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