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Alzheimer’s Disease Assessment Scale ADAS

Manzano JM, Llorca G, Ledesma A, et al [Spanish adaptation of the Alzheimer s disease assessment scale [ADAS]]. Actas Luso Esp Neurol Psiquiatr Cienc Afines 22 64-70, 1994... [Pg.690]

In a prospective study designed to investigate the pharmacodynamic effects of Uthium treatment on GSK-3 activity in patients with mild Alzheimer s disease, 71 patients received either lithium or a placebo for 10 weeks. Patients where assessed for cerebrospinal fluid (CSF) phospho-tau levels and cognitive function was assessed by Alzheimer s disease assessment scale (ADAS-Cog). No effect of lithium on CSF phosphorylated tau levels could be shown. However, a clinically significant effect on cognition was measured by ADAS-Cog [101]. It is feasible that a 10-week lithium treatment might not be sufficient to see an effect on phosphorylated tau or that GSK-3 inhibition will not be reflected in the CSF phospho-tau or total tau levels. CSF turnover is quite rapid (about 6 h) and a more predictive readout might be the tau/beta amyloid ratio that has been shown to be more sensitive [ 102]. [Pg.169]

Alzheimer s Disease Assessment Scale (ADAS) Structured interview 21 items total 11 items in the cognitive (COG) subset. 10 items in the noncognitive behavioral subset. Each subset may be scored separately from the total ADAS score Takes 45 minutes to administer the ADAS and 35 minutes for the ADAS-COG. The ADAS-COG refers to the cognitive assessment subset commonly used to measure cognitive function in clinical drug trials. Requires training for administration and scoring... [Pg.1130]

I Alzheimer s Disease Assessment Scale (ADAS-cog) tests multiple areas of cognitive decline. Error score 0-70. Low score=high performance. Usually a primary outcome variable. [Pg.143]

ADAS-cog Alzheimer s disease assessment scale, cognitive subscale... [Pg.26]

ADAS-Cog Alzheimer s Disease Assessment Scale - Cognitive Subscale... [Pg.54]

ADAS-COG Alzheimer s Disease Assessment Scale—Cognition ADRDA Alzheimer s Disease and Related Disorders Association apo E apolipoprotein E APP amyloid precursor protein /SAP beta-amyloid protein CYP450 cytochrome P450 enzyme system DSM-IV-TR Diagnostic and Statistical Manual of Mental Disorders, 4th ed.. Text Revision FAQ functional activities questionnaire MMSE mini-mental status exam NFT neurofibrillary tangle... [Pg.1171]

Adaptive tolerance, 1373 Adaptogen, 3503 Adaptogenic plants, 3648 ADAS-Cog. See Alzheimer s disease Assessment Scale-Cognitive Section (ADAS-Cog)... [Pg.4162]

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See also in sourсe #XX -- [ Pg.203 , Pg.254 ]



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