Allyl dextran

Sephacryl, a gel formed by cross-linking allyl dextran with N,N -methylenebisacrylamide, was introduced in the 1970s. The original Sephacryl... 

The performance of several Sephacryl gel combinations is illustrated by results achieved for glucans from different types of starch granules. The applied Sephacryl gels of Pharmacia Biotech (15) are cross-linked copolymers of allyl dextran and N,N -methylene bisacrylamide. The hydrophilic matrix minimizes nonspecific adsorption and thus guarantees maximum recovery. Depending on the pore size of the beads, ranging between 25 and 75 im in diameter, aqueous dissolved biopolymers up to particle diameters of 400 nm can be handled. 

TABLE 16.3 Producers (Pharmacia Biotech) Specification of Fractionation Ranges of Cross-Linked Allyl Dextran/N,N -Methylene Bisacrylamide Copolymer-Based Sephacryl Gels for Dextrans... 

Derivatized silica gel that is used for size-exclusion HPLC contains a proprietary bonded phase that is defined as hydrophilic to minimize nonspecific hydrophobic and ionic interactions. Polymeric supports consist of highly cross-linked agarose beads, with or without bonded dextran or cross-linked copolymers of allyl dextran and AyV -methylenebisacryl-amide. All supports are available with a variety of particle and pore sizes and distribution. 

Sephacryl HR is an allyl-dextran cross linked with bis-acrylamide. The gd partides have a diameter ranging from 25-75 pm and are mechanically very rigid. 

The trade names of the stationary phase media represent particular polymers formed under well-controlled conditions. Sephadex consists of dextran, cross-linked with epichlorohydrin in alkaline solution. Sephacryl is an allyl dextran, cross-linked with iV.iV -methylenebislacrylamide). Sepharose is a beaded form of agarose gel, where aggregates of the polysaccharide chains are formed. 

The bead structure of Sephaciyl is allyl dextran and fV.A -methylene bisacrylamide. 

Sephacryl S-100 high Resolution Allyl dextran and W,/V -methylene bisacryamide 50 3-11 n.a 1000-100,000 High resolution. Industrial scale applications AP Biotech... 

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