Allergy extrinsic allergic alveolitis

In type III or immunocomplex-mediated allergy, IgG antibodies form complexes with antigen. At low exposures, the body is able to remove diese complexes, but if there is a severe exposure, immunocomplexes release a variety of proinflammatory cytokines. The involvement of this mechanism is clearest in serum sickness. This mechanism is also considered to be most important in the development of extrinsic allergic alveolitis (hypersensitivity pneumonitis, especially... 

Baur, X. (1995) Hypersensitivity pneumonitis (extrinsic allergic alveolitis) induced by isocyanates. J. Allergy din. Immunol.. 95, 1004-1010... 

Besides respiratory allergies with hay-fever-like symptoms and asthma in atopic individuals, continuous occupational basidiospore exposure may result in hypersensitivity pneumonitis or extrinsic allergic alveolitis. The basidiomycetes Lentinus edodes, Pleurotus ostreatus, and Merulius lacrymans have all been shown to cause hypersensitivity pneumonitis from occupational exposure [26-28]. Actinomycetes in the compost used to grow button mushroom... 

O Brien IM, Bull J, Creamer B, Sepulveda R, Harries M, Bulge PS, Pepys J Asthma and extrinsic allergic alveolitis due to Merulius lacrymans. Clin Allergy 1978 8 535-542. 

Warren CP (1977) Extrinsic allergic alveolitis a disease commoner in non-smokers. Thorax 32(5) 567-569 Warren P, Cherniack RM, Tse KS (1974) Hypersensitivity reactions to grain dust. J Allergy Clin Immunol 53(3) 139-149 Warren CP, Tse KS, Cherniack RM (1978) Mechanical properties of the lung in extrinsic allergic alveolitis. Thorax 33 315-321... 

Eur Respir J 4 [Suppl 13] 47s-59s Salvaggio JE (1997) Extrinsic allergic alveolitis (hypersensitivity pneumonitis) past, present and future. Clin Exp Allergy 27 [Suppl l] 18-25... 

Tripathi A, Grammer LC (2001) Extrinsic allergic alveolitis from a proteolytic enzyme. Ann Allergy Asthma Immunol 86 425-427... 

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