Antimicrobial drugs allergic reactions

Every patient receiving antimicrobial therapy for skin and soft tissue infections must be monitored for efficacy and safety. Efficacy typically is manifested by reductions in temperature, white blood cell count, erythema, edema, and pain that begin within 48 to 72 hours. To ensure safety, dose antibiotics according to renal and hepatic function as appropriate, and monitor for and minimize adverse drug reactions, allergic reactions, and drug interactions. 

For both the clinician and patient, an allergic reaction elicited by a p-lactam antibiotic is probably considered the archetypal drug allergy but a range of other antibiotics, both naturally occurring and semisynthetic, and a number of other antimicrobials of varied origin and nature also... 

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