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Alkyl fluorides reduction with lithium aluminum hydride

Aryl and alkyl trimethylsilyl ethers can often be cleaved by refluxing in aqueous methanol, an advantage for acid- or base-sensitive substrates. The ethers are stable to Grignard and Wittig reactions and to reduction with lithium aluminum hydride at —15°. Aryl -butyldimethylsilyl ethers and other sterically more demanding silyl ethers require acid- or fluoride ion-catalyzed hydrolysis for removal. Increased steric bulk also improves their stability to a much harsher set of conditions. An excellent review of the selective deprotection of alkyl silyl ethers and aryl silyl ethers has been published. ... [Pg.273]

See also in sourсe #XX -- [ Pg.803 ]

See also in sourсe #XX -- [ Pg.8 , Pg.803 ]

See also in sourсe #XX -- [ Pg.8 , Pg.803 ]



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Alkyl fluorides

Alkyl lithium

Alkyl reduction

Alkylation lithium

Aluminum alkyls

Aluminum fluoride

Aluminum lithium with

Aluminum reduction

Aluminum reduction with

Fluoride alkylation

Fluorides, reduction

Hydride, aluminum reduction with

Lithium aluminum hydride, reduction

Lithium hydride reduction

Lithium reductions

Reduction alkylation

Reduction aluminum hydride

Reduction reductive alkylation

Reduction with hydrides

Reductions with lithium aluminum hydride

Reductive alkylation

With fluoride

With lithium, reduction

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