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Alkaloids hallucinogens

Peyote Mescal Mescal button Chemical/Pharmaceutical/Other Class A phe-nylethylamine derivative alkaloid hallucinogen found in the North American small, blue-green, spineless cactus Lophophora williamsii and in several South American cacti of the trichocereus species... [Pg.1624]

Problem 24.23 Which nitrogen atom in the hallucinogenic indole alkaloid jV,A -dimethyltryptamine is more basic Explain. [Pg.952]

Tryptamine-related hallucinogens are naturally occurring plant alkaloids or their chemically synthesized derivatives. Some of them are related to sub-... [Pg.212]

When looking for plants affecting serotoninergic neurotransmission, one might look into species that produce indole alkaloids, such alkaloids beingknown to impart to the plant s hallucinogenic properties. [Pg.74]

Table 4 Analytical Figures of Merit of the CL Kinetic-Based Determination of Drugs and Hallucinogenic Alkaloids Using the CAR Technique... [Pg.195]

Ingestion of hallucinogenic plant alkaloids and allied compounds does not always result in death. Many grazing animals display paresis, ataxia, dullness, and a tendency to isolate themselves from the herd. Some animals appear to act bizarre. Observations of such animal-plant interactions could have provided man with much information about hallucinogens. [Pg.10]

Other flavones in passionflower (vitexin, coumerin, umbelliferone) have not been well characterized for their neuropharmacological action. Vitexin (derived from millet in one study) was found to have antithyroid properties. The remaining constituents, maltol and harman alkaloids, are present in small quantities and not presumed to contribute to the psychotropic effects (Meier 1995). Harman alkaloids in greater quantities are hallucinogenic and presumed to work through 5-HT receptors (Grella et al. 1998). [Pg.238]

Little is known specifically about the effects of mescaline compared to LSD. Much information about it relies upon its similarities with other monoamine hallucinogens. The majority of attention is given here to mescaline, but some brief mention of the diverse effects of other peyote alkaloids (of which little is known) is deserved. Often, their effects are very different from mescaline. Many alkaloids are present in sufficent concentrations to alter human physiology after oral consumption of peyote. Lophophorine in humans causes a "sickening feeling in the back of... [Pg.361]

Cawe (Pachycereus pecten-aboriginum) is yet another species of hallucinogenic cactus, which grows in Mexico. It is also a columnar cactus, growing up to 35 feet in height. It is known as Cawe or Wichowaka to the Tarahumara. Studies have identfied 4-hydroxy-3-methoxyphenylethylamine and 4-tetrahydroisoquinoline alkaloids as the probable psychoactive constituents. [Pg.363]

There are two major types of hallucinogenic alkaloids in yage. These are DMT and the harmala alkaloids (or j8-carbolines). [Pg.364]

Based on structural similarities, the neuropharmacological mechanisms of morning glory alkaloids are likely similar or identical to those of LSD. The subjective effects are also similar, but the lower potency of the alkaloids requires larger doses for hallucinogenic effects. Somatic effects tend to be pronounced, with nausea and gastrointestinal symptoms being very common. [Pg.372]

The cholinergic hallucinogens all have common chemical constituents that are responsible for their pharmacological effects (Robbers et al. 1996). These are the tropane alkaloids hyoscyamine, scopolamine (or hyoscine), and atropine (figure 9.16). It is scopolamine, and not atropine or hyoscyamine, which primarily produces the central and hallucinogenic effects because it is the only one that passes the blood-brain barrier sufficiently. However, all three have peripheral effects. Datura stramonium contains 0.1-0.65% tropane alkaloids, which is principally... [Pg.392]


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