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Aldehydes naturally occurring

This aldehyde is identical with the naturally occurring phellandral, an aldehyde found in oil of water fennel. If the nitrosochloride of /3-phellandrene be decomposed by acetic acid, dehydrocuminic aldehyde and carvacrol result. [Pg.70]

The solubility of most metals is much higher when they exist as organometallic complexes.4445 Naturally occurring chemicals that can partially complex with metal compounds and increase the solubility of the metal include aliphatic acids, aromatic acids, alcohols, aldehydes, ketones, amines, aromatic hydrocarbons, esters, ethers, and phenols. Several complexation processes, including chelation and hydration, can occur in the deep-well environment. [Pg.799]

The formation of an aldehyde group on a macromolecule can produce an extremely useful derivative for subsequent modification or conjugation reactions. In their native state, proteins, peptides, nucleic acids, and oligonucleotides contain no naturally occurring aldehyde residues. There are no aldehydes on amino acid side chains, none introduced by post-translational modifications, and no formyl groups on any of the bases or sugars of DNA and RNA. To create reactive aldehydes at specific locations within these molecules opens the possibility of directing modification reactions toward discrete sites within the macromolecule. [Pg.129]

In contrast to other 2,5-anhydroaldoses (which exhibit mutarota-tion, possibly due to the formation of hemiacetals28), 2,5-anhydro-D-glucose does not show any mutarotation.27 The importance of this compound as a potentially useful precursor to C-nucleosides warrants a reinvestigation of the deamination reaction, and the definitive proof of the structure of the compound. The readily accessible 2,5-anhydro-D-mannose (11) does not possess the cis-disposed side-chains at C-2 and C-5 that would be required of a synthetic precursor to the naturally occurring C-nucleosides, with the exception of a-pyrazomycin (8). The possibility of an inversion of the orientation of the aldehyde group in 11 by equilibration under basic conditions could be considered. [Pg.116]

This imide system can also be used for the asymmetric synthesis of optically pure a,a-disubstituted amino aldehydes, which can be used in many synthetic applications.31 These optically active a-amino aldehydes were originally obtained from naturally occurring amino acids, which limited their availability. Thus, Wenglowsky and Hegedus32 reported a more practical route to a-amino aldehydes via an oxazolidinone method. As shown in Scheme 2 20, chiral diphenyl oxazolidinone 26 is first converted to allylic oxazolidinone 27 subsequent ozonolysis and imine formation lead to compound 28, which is ready for the a-alkylation using the oxazolidinone method. The results are shown in Table 2-6. [Pg.87]

The addition of allenyl metal reagents to aldehydes affords homopropargylic alcohols with contiguous OH- and Me-substituted stereocenters, which serves as a complementary approach to the aldol condensation for polyketide synthesis. Marshall has developed this method extensively and this work is the subject of a more detailed review (cf. Chapter 9) [50]. The applications of this method to the synthesis of naturally occurring compounds have also been wide-ranging and a few are highlighted below. [Pg.1073]

The carbohydrates are a group of naturally occurring carbonyl compounds (aldehydes or ketones) that also contain several hydroxyl groups. The carbohydrates include single sugars (monosaccharides) and their polymers, the oligosaccharides and polysaccharides. [Pg.34]

Naturally occurring antioxidants are present in many plants and trees such as hevea rubber. The first synthetic antioxidants were synthesized independently by Caldwell and by Winkelman and Gray by the condensation of aromatic amines with aliphatic aldehydes. [Pg.488]

Of the naturally occurring amino acids alanine only was prepared synthetically many years before it was discovered as a constituent of the protein molecule. Its name was given to it by its discoverer, Strecker, who prepared it in 1850 from aldehyde ammonia, which, when treated with hydrogen cyanide gives the aminocyanohydrin, and this by hydrolysis is then converted into the amino acid —... [Pg.30]

The first naturally occurring tricyclo[6.3.0.0 ]undecane to be synthesized was isocomene (757), a colorless oily sesquiterpene hydrocarbon isolated from several plant sources. In 1979, Paquette and Han reported an efficient, stereospecific approach starting with a preformed bicyclic enone, to which the third five-membered ring was appended with proper attention to stereochemistry and position of unsaturation (Scheme LXXX) The pivotal steps are seen to be the stannic chloride-induced cyclization of aldehyde 732 and the conjugate addition of lithium dimethylcuprate to 733 which sets the stereochemistry of the last methyl group. [Pg.72]

Several natural products and pharmaceuticals have been made in which a TPAP-catalysed oxidation of a primary alcohol to aldehyde step occurs, and these are listed in 2.1.3. They include agardhilactone, (-)-ceratopicanol, eleutherobin, (-)-eriolangin, (-)-eriolanin, okadaic acid, QS-21A p, cis- rapamycin, solamin and taxol syntheses. [Pg.37]

The full paper on the synthesis of onikulactone and mitsugashiwalactone (Vol. 7, p. 24) has been published.Whitesell reports two further useful sequences (cf. Vol. 7, p. 26) from accessible bicyclo[3,3,0]octanes which may lead to iridoids (123 X=H2, Y = H) may be converted into (124) via (123 X = H2, Y = C02Me), the product of ester enolate Claisen rearrangement of the derived allylic alcohol and oxidative decarboxylation/ whereas (123 X = 0, Y = H) readily leads to (125), a known derivative of antirride (126) via an alkylation-dehydration-epoxi-dation-rearrangement sequence. Aucubigenin (121 X = OH, R = H), which is stable at —20°C and readily obtained by enzymic hydrolysis of aucubin (121 X = OH, R = j8-Glu), is converted by mild acid into (127) ° with no dialdehyde detected sodium borohydride reduction of aucubigenin yields the non-naturally occurring isoeucommiol (128 X=H,OH) probably via the aldehyde (128 X = O). ... [Pg.36]

In a similar manner, intramolecular cyclization of the O-stannyl ketyl derivatives 201 and 206, generated from the oxazolyl aldehydes 200 and 205, provides a facile method for the chiral synthesis of 3-hydroxy-2-(hydroxymethyl)-5-substimted-pyrrolidines 202 and 203 and the piperidine analogues 207 and 208 that can be successfully transformed into naturally occurring amino alcohols, (+)-bulgecinine 204 and (—)-desoxoprosopinine 209, respectively (Fig. [Pg.29]

Substituted chiral aldehydes can be derivatized with naturally occurring (1/ ,2S)-ephedrine to give oxazolidines, UC- and H-NMR analysis allows determination of the enantiomeric excess and in simple cases the absolute configuration of the analyzed aldehyde6. Very mild reaction conditions are required. [Pg.278]


See other pages where Aldehydes naturally occurring is mentioned: [Pg.325]    [Pg.325]    [Pg.305]    [Pg.497]    [Pg.501]    [Pg.475]    [Pg.476]    [Pg.304]    [Pg.238]    [Pg.184]    [Pg.980]    [Pg.427]    [Pg.247]    [Pg.62]    [Pg.87]    [Pg.323]    [Pg.249]    [Pg.117]    [Pg.70]    [Pg.191]    [Pg.553]    [Pg.427]    [Pg.500]    [Pg.344]    [Pg.93]    [Pg.568]    [Pg.1076]    [Pg.131]    [Pg.361]    [Pg.88]    [Pg.177]    [Pg.257]    [Pg.1532]    [Pg.57]    [Pg.212]    [Pg.311]    [Pg.323]    [Pg.403]   
See also in sourсe #XX -- [ Pg.709 ]

See also in sourсe #XX -- [ Pg.709 ]

See also in sourсe #XX -- [ Pg.709 ]

See also in sourсe #XX -- [ Pg.659 ]

See also in sourсe #XX -- [ Pg.731 ]

See also in sourсe #XX -- [ Pg.692 ]




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Natural Occurence

Naturally Occurring Aldehydes and Ketones

Naturally-occurring

Nature aldehydes

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