Ipratropium Albuterol

Albuterol/ipratropium inhaler 2 puffs every 6 hours Glipizide 10 mg once daily Hydrochlorothiazide 25 mg once daily Lisinopril 20 mg once daily... 

Albuterol Ipratropium (Combivent, DuoNeb) [Bronchodilator/Adrenergic, Anticholinergic] Uses coPD ... 

Inhalant 90 mcg/puff aerosol 0.021, 0.042, 0.083, 0.5, 0.63% solution for nebulization Oral 2,4 mg tablets 2 mg/5 mL syrup Oral sustained-release 4, 8 mg tablets Albuterol/Ipratropium (Combivent, DuoNeb)... 

Albuterol (Proventil, Ventolin, Volmax) Albuterol Ipratropium (Combivent, Duoneb) Aminophylline Aiformoterol (Brovana) Ephedrine... 

Nebulized short-acting bronchodilator therapy (e.g., albuterol and ipratropium)... 

Albuterol 2.5-5 mg nebulized every hour ° Ipratropium 500 meg nebulized every hour ° Continue therapy for 1-3 h, provided there is improvement ° Consider corticosteroid... 

Albuterol 2.5-5 mg nebulized every hour ° Ipratropium 500 meg nebulized every hour... 

Ipratropium with albuterol MDI 1 8 mcg/puff of ipratropium bromide and 90 mcg/puff of albuterol 2-3 puffs every 6 hours 1-2 puffs every 8 hours... 

The addition of ipratropium bromide to inhaled p2-agonist therapy in acute severe asthma improves pulmonary function and decreases hospitalization rates in both adult and pediatric patients.31 The benefit of combining ipratropium and albuterol appears to be greatest in moderate to severe exacerbations, and the combination should be considered first-line therapy in severe exacerbations. 

MDI 18 meg of ipratropium bromide and 90 meg of albuterol per puff 4-8 puffs as needed 4-8 puffs as needed... 

Albuterol is the preferred bronchodilator for treatment of acute exacerbations because of its rapid onset of action. Ipratropium can be added to allow for lower doses of albuterol, thus reducing dose-dependent adverse effects such as tachycardia and tremor. Delivery can be through metered-dose inhaler (MDI) and spacer or nebulizer. The nebulizer route is preferred in patients with severe dyspnea and/or cough that would limit delivery of medication through an MDI with spacer. If response is inadequate, theophylline can be considered however, clinical evidence supporting its use is lacking. 

Ipratropium metered dose inhaler (MDI) 2 puffs every 6 hours Albuterol MDI 2 puffs every 4 hours as needed Prednisone 10 mg daily Diclofenac 75 mg two times a day Aspirin 81 mg daily... 

Ipratropium bromide has a slower onset of action than short-acting /J2-agonists (15 to 20 minutes vs. 5 minutes for albuterol). For this reason, it may be less suitable for as-needed use, but it is often prescribed in this manner. Ipratropium has a more prolonged bronchodilator effect than short-acting /l2-agonists. Its peak effect occurs in 1.5 to 2 hours and its duration is 4 to 6 hours. The recommended dose via MDI is two puffs four times a day with upward titration often to 24 puffs/day. It is also available as a solution for nebulization. The most frequent patient complaints are dry mouth, nausea, and, occasionally, metallic taste. Because it is poorly absorbed systemically, anticholinergic side effects are uncommon (e.g., blurred vision, urinary retention, nausea, and tachycardia). 

A combination product containing albuterol and ipratropium (Combi-vent) is available as an MDI for chronic maintenance therapy of COPD. Other similar combination products may become available in the future. 

Rx Albuterol sulfate and ipratropium bromide inhalation solution ... 

Inhalation solutions are designed to deliver a drug into the respiratory tree of a patient for a local or systemie effect. Examples of compounded inhalation solutions (Table 9) include individually and in combinations of albuterol, cromolyn, morphine sulfate, corticosteroids, ipratropium, metaproterenol, terbutaline, and others. 

Solution incompatibility Advise patients that ipratropium inhalation solution can be mixed in the nebulizer with albuterol or metaproterenol if used within 1 hour. 

Aerosol Each actuation delivers 18 meg ipratropium bromide and 103 meg albuterol sulfate Rx) Combivent (Boehringer Ingelheim)... 

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