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Albuterol sulfate

ALBUTEROL SULFATE INHALATION SOLUTION 20ML BOTTLE WITH DROPPER 6505012579963 BT 10 41 ... [Pg.404]

Rx Albuterol sulfate and ipratropium bromide inhalation solution ... [Pg.34]

Aerosol Each actuation delivers 18 meg ipratropium bromide and 103 meg albuterol sulfate Rx) Combivent (Boehringer Ingelheim)... [Pg.766]

Inhalation solution 0.5 mg ipratopium bromide and 3 mg albuterol sulfate (equiv. to 2.5 mg albuterol base) DuoNeb (Dey)... [Pg.766]

The effects of extreme temperatures on drug delivery of two albuterol sulfate hydrofluoroalkane (HFA) MDIs were evaluated. Three Proventil HFA and three Ventolin HFA MDIs were stored at room temperature and served as controls, while three of each product were placed in the trunk of a vehicle in Tuscon, Arizona. The temperature of the vehicle was monitored for six months. Product performance for each of the MDIs was evaluated at room temperature. An additional study was performed to investigate the performance of the two products when actuated at 4, 22, 47, and 60°C. Within one week of being placed in the test vehicle, all MDI... [Pg.671]

Hoye, W. L., Mogalian, E. M., and Myrdal, P. B. (2005), The effects of extreme temperatures on drug delivery of albuterol sulfate hydrofluoroalkane inhalation products, Am. J. Health-Syst. Pharm., 62(21), 2271-2277. [Pg.684]

AccuNeb (albuterol sulfate) inhalation solution is supplied in two strengths in unit-dose vials. Each unit-dose vial contains either 0.75 mg of albuterol sulfate (equivalent to 0.63 mg of albuterol) or 1.50 mg of albuterol sulfate (equivalent to 1.25 mg of albuterol) with sodium chloride and sulfuric acid in a 3-mL isotonic, sterile, aqueous solution. Sodium chloride is added to adjust isotonicity of the solution, and sulfuric acid is added to adjust the pH of the solution to 3.5. [Pg.71]

Proventil Albuterol sulfate Oleic acid CFC 11, CFC 12 Suspension ... [Pg.231]

Proventil HFA Albuterol sulfate Oleic acid HFA 134a, ethanol Suspension 1.96 13, 14... [Pg.231]

Ward, G.H. and Schultz, R.K. (1995). Process-induced crystallinity changes in albuterol sulfate and its effect on powder physical stabilit harm. Res., 12 773-779. [Pg.566]

Proventil HFA (3M) Albuterol sulfate August 1996 HFA 134a, ethanol, oleic acid Suspension... [Pg.692]

Ventolin HFA Albuterol sulfate April 2001 HFA 134a Suspension... [Pg.692]

Pro air HFA Albuterol sulfate October 2004 HFA 134a, ethanol Suspension... [Pg.692]

Alternatively, protein particles can be produced using a supercritical or near critical C02-assisted aero-solization and bubble drying process. This method utilizes the high solubility of CO2 in water, coupled with expansion of the solution through a nozzle to aerosolize aqueous solutions of drugs. When the microbubbles formed are dried, solid (such as lactose and albuterol sulfate, with size between 0.5 pm and... [Pg.1429]

Chisty MNA, Bellantone RA, Taft DR, Plakogiannis FM. In vitro evaluation of the release of albuterol sulfate from polymer gels effect of fatty acids on drug transport across biological membranes. Drug Dev Ind Pharm 2002 28(10) 1221—1229. [Pg.407]

Albuterol sulfate (360-900 pg) and pirbuterol acetate (600 (xg) are potent, short-acting 32 adrenergic agents that rapidly produce bronchodilatation... [Pg.313]

Albuterol sulfate P2 agonist short 360 (i,g 5 1-3 Equine Aerosol Delivery Device (Derksen... [Pg.313]

In humans, the half-life of aerosolized albuterol sulfate is approximately 4 h. The kidney is the primary site of elimination with the majority of the drug excreted as sulfide and glucuronide metabolites (61%) and the remainder (39%) excreted unchanged. The absorption of albuterol from the gastrointestinal tract is poor (20% bioavailability) the primary site of absorption into the systemic circulation is the pulmonary system. There are currently no data available on the pharmacokinetics of albuterol in horses. [Pg.314]

Most albuterol sulfate preparations contain an equimolar, racemic mixture of the (R)- and (S)-stereoisomers (Page Morley 1999). (R)-albuterol has bronchodilator and bronchoprotec-tive activity. (S)-Albuterol does not activate P2 adrenoceptors and does not modify the activation of these receptors by (R)-albuterol. (S)-Albuterol is metabolized more slowly than (R)-albuterol and is retained preferentially in the airways. Until recently, (S)-albuterol was considered biologically inert however, it has been shown to intensify allergic bronchospasm and eosinophilic activation in laboratory animals and appears to have the potential to induce paradoxical reactions in some asthmatic patients. In horses, (S)-albuterol does not have bronchodilatory activity and stimulates acetylcholine release via prejunctional 2 adrenoceptor stimulation (Zhang et al 1998). Levalbuterol (homochiral (R)-albuterol) has been marketed recently and reportedly dramatically reduces the incidence of the side-effects associated with racemic albuterol in some patients. [Pg.314]

The combination of albuterol sulfate and ipratropium bromide is available commercially in a metered-dose inhaler device for humans. In human patients with chronic obstructive pulmonary disease, this anticholinergic p2 agonist combination provides more complete bronchodilatation than... [Pg.316]

The magnitude and duration of drug concentrations above MIC in respiratory secretions after aerosol administration indicate that mhalation therapy may be a suitable option for some bacterial infections of the lower respiratory tract. Pretreatment with a short-acting, aerosolized bronchodilator, such as albuterol sulfate, may improve the pulmonary distribution of aerosolized antimicrobial drugs. [Pg.323]


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