Captopril Albumin

ANTI HYPERTENSIVES AND HEART FAILURE DRUGS ALBUMIN-CONTAINING SOLUTIONS Acute 1 BP following rapid infusion with captopril or enalapril Uncertain at present Use alternative colloids monitor BP closely while on infusion... 

The administration of total parenteral nutrition for periods greater than 1 week induces cholestatic changes and nonspecific enzyme elevations in some patients. Patients with low serum albumin concentrations may be at greater risk than patients with normal serum albumin concentrations. This reaction also has been reported to occur rarely with sulfonamides, sulfonylureas, erythromycin estolate and ethylsuccinate, captopril, fisinoprU, and other phenothiazines. ... 

Acute hypotension has been seen in a few patients taking enalapril when they were given a rapid infusion of albumin-containing stable plasma protein solution (SPPS). Another case occurred in an infant taking captopril when given albumin 4%l A few other cases have been described with gelatin-type colloids in patients taking ACE inhibitors (cilazapril, enalapril, lisinopril). 

A 20-month-old infant taking captopril was haemodynamically stable for 35 minutes after induction of anaesthesia while awaiting a donor kidney, but then developed hypotension after a holus dose of 20 mL of albumin 4% (Albumex) was given. This was reversed with dopamine infusion. ... 

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