Albino mutation

Jackson, I. J. and Bennett, D.C. (1990). Identification of the albino mutation of mouse tyrosinase by analysis of an in vitro revertant. Proc. Natl. Acad. Sci. USA 87 7010-7014. 

Yokoyama, T., Silversides, D. W., Waymire, K. G., Kwon, B. S., Takeuchi, T., and Overbeek, P. A. (1990). Conserved cysteine to serine mutation in tyrosinase is responsible for the classical albino mutation in laboratory mice. Nucleic Acids Res. 18 7293-7298. 

Koga A, Inagaki H, Bessho Y, Hori H (1995) Insertion of a novel transposable element in the tyrosinase gene is responsible for an albino mutation in the medaka fish, Oryzias latipes. Molec Genl Genet 249 400-405. 

Shibahara, S.,Okinaga,S.,Tomita, Y.,Takeda, A., Yamamoto, H., Sato, M.,andTakeuchi, T. (1990). A point mutation in the tyrosinase gene of BALB/c albino mouse causing the cysteine-serine substitution at position 85. Eur. J. Biochem. 189 455-461. 

Host-mediated assay, E. coli K-12/343/113 forward mutation (VAL ) in male Swiss albino mouse liver and spleen in vivo Host-mediated assay, E. coli K-12 uvrBIrecA and (differential... 

Neostriatal dopamine depletion and locomotor abnormalities due to the Albino Swiss rat agu mutation. Neurosci Lett 213 173—176. 

Odeigah PGC. 1997. Sperm head abnormalities and dominant lethal effects of formaldehyde in albino rats. Mutat Res 389 141-148. 

Other workers have also noted non-reactivity in Wistar rats [12, 216] and West [671, 672] reported its occurrence in both brown and black wild rats. It was suggested that the mutation to non-reactivity in Wistar albino stocks may have arisen by chance crosses with these wild rats however, it is also possible that non-reactivity to egg-white and dextran may have arisen in different colonies through spontaneous mutations. The incidence of non-reactivity in one colony of Wistar albino rats is reported to be on the increase [30] but the significance of this is unknown although natural selection cannot be excluded. In this context, it may be significant that non-reactors are relatively more, resistant than reactors to traumatic and tourniquet shock [206] and also to anaphylaxis, pain and thermal oedema [32, 205, 590]. Moreover, although intravenously injected histamine produces hypotension in both reactor and non-... 

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