4-methoxycarbonyl-5-phenyl

Thiophen 3-Cyan-4-hydroxy-5-methoxycarbonyl-2-phenyl- E6a, 296 [HS-CH2-COOR +... 

Method B 2-Amino-4-tolyl 2-(methoxycarbonyl)phenyl sulfide (273 g, 1 mol) was heated at 215-230JC for 1 h under N2 and MeOII was allowed to distill off. The mixture was heated at this temperature under vacuum for a further 30 min, cooled to 100°C, diluted with EtOH (400 mL) and refluxed for 1 h. The mixture was cooled and the solid product was collected and recrystallized (EtOH, 400 mL), giving colorless crystals yield 217 g (90%) mp 288 -290 C. 

N-(tert-Butoxycarbonyl)-P-4-(methoxycarbonyl)phenyl]alanine methyl ester L-Phenylalanine, N-[(l,l-dimethylethoxy)carbonyl]-4-(methoxycarbonyl)-, methyl ester (160168-19-4)... 

CijHijNOj 83073-63-6) see Tilisolol hydrochloride l-methyl-2-[[4-(methoxycarbonyl)phenyl]methyl]-l,2-hy-drazinedicarboxylic acid bis(phenylmethyl) ester (CifiHjgNjOg) see Procarbazine 5-methyl-8-methoxycoumarin... 

Pyrrolizin-3-ones may also be obtained by FVP of 3-(pyrrol-2-yl)propenoate esters such as 62, 69, and 74. Also, benzo-annulated pyrrolizinone 17 was obtained by FVP of 2-(tf-methoxycarbonyl phenyl (pyrrole <1999J(P1)2047>. FVP of alcohols 77, 78, and 79 led to 3//-pyrrolyzine derivatives 1, 192, and 193, respectively, in good yields (66-95%). These transformations proceed by elimination of water and subsequent electrocyclization of the in situ-generated cumulene (Scheme 44) <1999J(P1)2049>. 

Dihydro-4,5-dimethyl-3-(hydroperoxy)-2-[4-(methoxycarbonyl)phenyl]isothiazole 1,1-dioxide (AFUPOG) 1.461 1.417 106.6 97... 

Through the in situ deprotection of A-acyl-2-(trimethylsilyl)ethynylanilines 465 followed by palladium-catalyzed cyclization-methoxycarbonylation, stereoisomeric 4-methoxycarbonylmethylene-3,l-benzoxazine derivatives 466 and 467 were obtained (Equation 51). The (Z)-isomers 466 were consistently found to be the main product, with the exception of the -(methoxycarbonyl)phenyl-substituted compounds (R = H, = C6H4C02Me(/>)), for which a... 

Cyclization of the 2-halomethyl-3-[2-(methoxycarbonyl)phenyl]quin-azolin-4(3//)-one (688) with ammonia or primary amines led to the formation of 6-substituted-6,7-dihydroquinazolino[3,2-a] 1,4-benzodiaze-pine-5,13(5//, 13/f)-diones (689) [77JHC1191 79GEP(0)2758875],... 

Pentanoate (4-Methoxycarbonyl-phenyl) Octafluoro-5H- ElOb, 206 (Educt)... 

N-Dimethylstibano- XIII/8, 511 N-(2-Methoxycarbonyl-phenyl)-N-organo- E4, 353 (R-NCO +Amin)... 

Telluran Brom-(2-methoxycarbonyl-phenyl)- EI2b, 244 (Te —C6H3 - TeBr)... 

Hydroxy-2-oxo-3-phenyl-2,5-dihydro- VI/2, 688 4-Hydroxy-5-oxo-4-phenyl-4,5-dihydro- X/4, 839 Keten Methoxycarbonyl-phenyl-VII/4, 81, 90... 

Triazen 3-Hydroxymethyl-1-(4-methoxycarbonyl-phenyl)-3-methyl- E16a, 1203 (Ar —Nf + Amin)... 

Ethoxycarbonyl-methyl)-l-(4-methoxycarbonyl-phenyl)- Elba, 1189 (Ar — Nf + Amin) 2H-l,2,3-Triazol 2-Phenyl-4-(1,2,3,4-tetrahydroxy-butyl)-IV/la, 896... 

Raney nickel) of the potassium salt of D-xy/o-5-hexulosonic acid oxime produces a mixture of 5-amino-5-deoxy-L-idonic and -D-glu-conic acid in the ratio of 2 1, which is converted into the methyl ester hydrochloride. Upon treatment with alkali, spontaneous cyclization to the pair of 1,5-lactams occurs. 5-Amino-5-deoxy-L-idono-l,5-lactam and 5-amino-5-deoxy-D-glucono-l,5-lactam were separated by recrystallization. The optical rotatory dispersion curves of both compounds were discussed. A new type of lactam, namely, 2-enamino-N,N -bis[(p-methoxycarbonyl)phenyl]-4-(D-gaiacfo-penta-acetoxypentyl)-4-butanelactam was prepared by tbe reaction of 5,6,7,8,9-penta-0-acetyl-3,4-dideoxy-D-ga/ocfo-nonulos- rcns-3-en-l-onic acid with methyl p-aminobenzoate. 

Time-resolved IR studies of the photolysis of 2-(methoxycarbonyl)phenyl azide in solution at room temperature showed that the didehydroazepine (47) was the sole intermediate, at least on the ps time-scale. This contrasts with photolysis of the same compound in matrices at 10 K, where the nitrene, iminoketene (48) and azetinone (49) were observed as well as (47). Matrix photolysis of 2-hydroxy-phenyl azide gives at least three major products, all of which are photo-interconvertible. Two of these are identified as the EtZ mixture of iminodi-enones (50), while the third is the ring-opened compound (51), existing as a mixture of conformers. 2-Aminophenyl azide behaves in a similar manner. Rapid H-transfer from the ortho hydroxy or amino group to the nitrene centre in each case appears to suppress ring expansion completely. 

Photolysis (quartz vessel, 35 °C, sixteen 8-W low-pressure mercury lamps) of methyl 2,3,3-triphenyloxirane-2-carboxylate (la) or methyl 2,3-diphenyloxirane-2-carboxylate (lb) effected a ring cleavage to benzophenone (benzaldehyde) and methoxycarbonyl(phenyl)carbene which underwent [2-t-l] cycloaddition to alkenes, e.g. formation of 2 from la and lb with 2,3-dimethylbut-2-ene. ... 

Diene generation followed by a Diels-Alder reaction can be carried out as a one-pot reaction. Methyl 9-(3-cyclopropylcyclobut-2-enyl)nonanoate was heated with dimethyl acetylenedicarboxylate, ring opening of the cyclobutene resulted followed by cyclohexene formation due to dienophile trapping of the buta-1,3-diene intermediate giving methyl 9-[5-cyclo-propyl-2,3-bis(methoxycarbonyl)phenyl]nonanoate after oxidation. ... 

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