Agrochemical regulation

However, Silent Spring , Rachel Carson s challenge to the perceived abuse of synthetic pesticides, published in 1962, initiated the a movement toward strict agrochemical regulation and the far more rigorous assessment of risks and benefits from pesticide use. 

Herbicides are also sometimes classified according to mode of action, selectivity, registered uses, and toxicity. The ever-increasing importance of herbicides and other pesticides and agrochemicals to a wide range of users, regulators, and researchers has led to the development of multiple and extensive computer databases. The primary database resources contain collected information relevant to herbicides, and numerous resource pubHcations are available to those needing information on the various aspects of herbicides (2). 

G- - Marco, R. M. Holhngworth, and. R. Plimmer, eds.. Regulation of Agrochemicals A Driving Force in Their Evolution, Ametican Chemical Society, Washington, D.C., 1991, 188 pp. 

Nehez M, Boros P, Ferke A, et al. 1988. Cytogenetic examination of people working with agrochemicals in the southern region of Hungary. Regul Toxicol Pharmacol 8 37-44. 

Health, Environmental, Quarantine and Other Regulations Many countries have strict regulations designed to protect the ecosystem and agrochemical business. For example any matrix material derived from pork, beef, sheep or horse tissue has to be accompanied with a Veterinary Certificate confirming that the matrix material is free of certain specified diseases before it can be imported into the EU. The Australian import restrictions are even tougher and require the importer to obtain prior permission to import plant and animal materials and products derived from biological materials. To get an import license it is necessary to complete an application, which includes information from the producer about the actual production process used to prepare the matrix ... 

J.N. Seiber, Analytical chemistry and pesticide regulation, in Regulation of Agrochemicals. A Driving Force in their Evolution, ed. G.J. Marco, R.M. Hollingworth, and J.R. Plimmer, American Chemical Society, Washington, DC, Chapt. 10 (1991). 

Field residue data, which are generated to meet requirements in the pesticide registration process, are used to regulate the use of agriculture products within the European Union (EU). This article examines the best practices to conduct crop field trials and to generate crop residue samples in Europe in order to provide part of the data that the agrochemical producers of the active ingredients must provide to the EU Commission. 

A.G. Hackett, Chloroacetanilides in Metabohc Pathways of Agrochemicals Part 1 Herbicides and Plant Growth Regulators, ed. T. Roberts, Royal Society of Chemistry, Cambridge, pp. 179-218(1998). 

As already mentioned, the most important industrial application of homogeneous hydrogenation catalysts is for the enantioselective synthesis of chiral compounds. Today, not only pharmaceuticals and vitamins [3], agrochemicals [4], flavors and fragrances [5] but also functional materials [6, 7] are increasingly produced as enantiomerically pure compounds. The reason for this development is the often superior performance of the pure enantiomers and/or that regulations demand the evaluation of both enantiomers of a biologically active compound before its approval. This trend has made the economical enantioselective synthesis of chiral performance chemicals a very important topic. 

Quality and regulation are the most significant differentiators between the Pharmaceutical sector and the Specialty Chemical and Agrochemical sectors all of which employ the same basic production equipment and batch manufacturing techniques. 

Marine fauna and flora, then, show great promise as a source of leads to new agrochemically useful plant growth regulators or insect control agents. 

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