Aggregation structure Terms Links

Hair is composed of approximately 65 to 95% protein, 1 to 9% lipid, and small quantities of trace elements, polysaccharides, and water. - - The majority of hair protein is often referred to as keratin, which is a general term used to describe aggregates of protein with low or high sulfur content. These proteins are synthesized in the keratogenous zone of the hair follicle as matrix cells move upward from the hair bulb to form layers of the hair shaft. The cuticle, cortex, and medulla are comprised largely of keratin, although it is structurally different in each layer. Keratin in the exocuticle contains a high concentration of cysteine, which forms disulfide bonds which link the A-layer to the exocuticle, and this makes the cuticle... 

HA plays an extremely important structural role in cartilage and other connective tissues. For instance, the most important cartilage proteoglycan (PG), termed aggrecan, is bound specifically to HA chains with the help of special link proteins. The formed aggregates have masses of about 100 MDa and are deposited within the collagen framework in a highly ordered manner [64]. 

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