Agglutination aggregates

Agglutination. The aggregation of bacterial cells into agglutinates enabling phagocytes to eliminate these cells rapidly firm the body. 

They link single-celled pathogens into aggregates (immune complexes), which are more easily taken up by phagocytes (agglutination). 

AGGLUTINATION. The combination or aggregation of particles of matter under the influence of a specific protein. The term is usually restricted to antigen-antibody reactions characterized by the clumping together of visible cells such as bacteria orerythrocytes. 

AGGREGATION. Tins overall operation may be considered to include the more specific designations of agglutination, coagulation, and flocculation. These terms imply some change in the state of dispersion of sols or of macromolecules in solution. 

Recently, Jaffe and Deykin (16) presented evidence for a structural requirement for collagen-induced platelet aggregation. They found that particulate, salt-precipitated collagen was inactive in terms of platelet agglutination and that soluble monomeric collagen resulted in platelet agglutination only after a lag of about 3 min. Soluble microfibrillar... 

Agglutination. Bacterial cells may be aggregated by binding to antibodies that mask negative ionic surface charges and cros.s-link cellular structures (Fig. 7-8). The bacteria are thus immediately immobilized. This limits their ability to maintain an infection, but it forms a particulate matrix. This type of complex must also undergo elimination through the reticuloendothelial system. 

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