Agents for Diagnostic Imaging

The radionuclide at the beginning of the decay sequence is referred to as the parent, and the radionuclide produced by the decay is referred to as the daughter, which may be stable or radioactive. There are five types of radioactive decay, distinguished according to the nature of the primary radiation event. A radioactive nucleus may decay by more than one riKthod. The dominant method at any given time depends on such factors as the size of the nucleus and the balance of protons and neutrons. The types of decay described below are in order of how commonly they are u.sed in current diagnostic nuclear medicine practice  

Isomeric Iransitian (IT). Isomeric transition is a decay process involving neither the emission nor the capture of a panicle. The nucleus simply changes from a higher to a lower energy level by emitting y-rays. Therefore, both mass number and atomic 

Beta-particle emission Ifi ) The nucleus emits a negativecl -Iron when a neutron changes to a proton. A y-ray may vr tiu) not accompany the emission of a fi panicle. 

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Chan, K.W.Y. and Wong, W.T. (2007) Small molecular gadolinium(III) complexes as MRI contrast agents for diagnostic imaging. Coordination Chemical Reviews, 251, 2428-2451. 

Plasmon-Resonant Gold Nanorods as Multifunctional Agents for Diagnostics, Imaging, and Photothermal Therapy... 

Iodine-124 Accelerator PET agent for diagnostic imaging with labelled compounds... 

E.G. Schutt, D.H. Klein, R.M. Mattrey, J.G. Riess, Injectable microbubbles as contrast agents for diagnostic ultrasound imaging The key role of perfluorochem-icals, Angew. Chem. Int. Ed. 42 (2003) 3218-3235. 

Anderson CJ, Welch MJ. Radiometal-labeled agents (non-techne-tium) for diagnostic imaging. Chem. Rev. 1999 99 2219-2234. 

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