Affinity capillary electrophoresis-mass spectrometry

Dunayevskiy, Y.M., Lyubarskaya, Y.V., Chu, Y.-H., Vouros, P., Karger, B.L. Simultaneous measurement of nineteen binding constants of peptides to vancomycin using affinity capillary electrophoresis-mass spectrometry. J. Med. Chem. 1998, 41, 1201-1204. 

Kirby, D.P., Vouros, P., Karger, B.L. Affinity capillary electrophoresis-mass spectrometry for screening combinatorial libraries. J. Am. 

YH Chu, YM Dunayevskiy, DB Kirby, P Vouros, BL Karger. Affinity capillary electrophoresis—mass spectrometry for screening combinatorial libraries. J Am Chem Soc 118 7827-7835, 1996. 

YV Lyubarskaya, YM Dunayevskiy, P Vouros, BL Karger. Microscale epitope mapping by affinity capillary electrophoresis-mass spectrometry. Anal Chem 69 3008-3014, 1997. 

YH Chu, DP Kirby, BL Karger. Free-solution identification of candidate peptides from combinatorial libraries by affinity capillary electrophoresis/mass spectrometry. J Am Chem Soc 117 5419-5420, 1995. 

Cheng CC, Chu YH, Affinity capillary electrophoresis-mass spectrometry in combinatorial library screening, Am. Lab., 30 79-81, 1998. 

Affinity Capillary Electrophoresis-Mass Spectrometry. Affinity capillary electrophoresis was originally used for the determination of the binding constants of small molecules to proteins (47-49). This solution-based technique is rapid and requires only small amounts of ligands. Affinity constants are measured based on the mobility change of the ligand on interaction with the receptor present in the electrophoretic buffer (50). By combining affinity capillary electrophoresis with on-line mass spectrometric detection and... 

Chu, Y-H. Kirby, D.P Karger, B.L. Free Solution Identification of Candidate Peptides from Combinatorial Libraries by Affinity Capillary Electrophoresis/ Mass Spectrometry, J. Am. Chem. Soc. 117, 5419-5420 (1995). 

Lyubarskaya, Y.V Dunayevskiy, Y.M. Vouros, R Karger, B.L. Microscale Epitope Mapping by Affinity Capillary Electrophoresis-Mass Spectrometry, Anal. Chem. 69,3008-3014 (1997). 

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