Aesculus hippocastaneum

The horse chestnut, Aesculus hippocastaneum (Hippocastanaceae), was introduced into the northern Europe from the Near East in the 16th century. Extracts from horse chestnut seeds were already being used therapeutically in France in the early 1800s. Several French works published between 1896 and 1909 reported successful outcomes in the treatment of hemorrhoidal ailments (100). Traditionally, horse chestnut has been used for the treatment of varicose veins, hemorrhoids, phlebitis, diarrhea, fever, and enlargement... 

Lorenz D, Marek ML. Das therapeutische wirksame Prinzip der Rosskastanie (Aesculus hippocastaneum). Arzneim Forsch/Drug Res 1960 10 263-272. 

Five other species of Aesculus were negative Aesculus assamia, A. hippocastaneum, A. parviflora, A. pavia, Aesculus sp. 

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