Adenosine-5’-monophosphate leukocytes

Theophylline and aminophylline may produce bronchodilation by inhibition of phosphodiesterase (thereby increasing cyclic adenosine monophosphate levels), inhibition of calcium ion influx into smooth muscle, prostaglandin antagonism, stimulation of endogenous catecholamines, adenosine receptor antagonism, and inhibition of release of mediators from mast cells and leukocytes. 

A significant hereditary component to the ocular disease has been noted among patients with either a personal or a family history of atopic dermatitis. Abnormalities in IgE production, leukocyte cyclic adenosine monophosphate response, and abnormal methacholine... 

Colchicine with its microtubule-disrupting properties limits the chemotactic and phagocytic activity of polymorphonuclear lymphocytes. It also induces the release of prostaglandin E, a suppressor of leukocyte function by increasing the level of cyclic adenosine monophosphate [39]. Furthermore, the ability of colchicine in inhibition of IL-1 production and histamine release makes it an excellent drug for a number of dermatitis-related complexities like psoriasis, Behget s syndrome, recurrent aphthous stomatitis, leukocytoclastic vasculitis and urticarial vasculitis, bullous disease, scleroderma, fibromatosis. Sweet s syndrome, amyloidosis, and many more [40]. 

AChE, BuChE, AChE molecular forms, lactate, p02, PCO2, carboxyles-terase (EC 3.1.1.1), alkaline phosphatase (EC 3.1.3.1), aspartate aminotransferase (AST, EC 2.6.1.1), alanine aminotransferase (ALT, EC 2.6.1.2), 7-glutamyltransferase (7-GT, EC 2.3.2.2), lactatedehydrogenase (LDH, EC 1.1.27), number of leukocytes (No leuco), corticosterone (CS), cyclic adenosine and guanosine monophosphate (cAMP, cGMP), OP metabolites (in case of parathion and fenitrothion), phosphonyl moiety attached to the enzyme in case of sarin (phosph. moiety), number of erythrocytes (No RBC), and tyrosine aminotransferase (TAT, EC 2.6.1.5), respectively. 

The differentiation between chemokinesis (increase of spontaneous movement) and chemotaxis (increase of directed movement) might also be of importance [274], Thus, dibutyryl cyclic adenosine 3, 5 -monophosphate produces divergent effects upon the two parameters of leukocyte locomotion under certain conditions [275] consequently it would seem that leukocyte movement should include measurements of both chemokinesis and chemotaxis. It is also noteworthy that too large a... 

Bourne, H. R., Melmon, K. L., and Lichtenstein, L. M., 1971, Histamine augments leukocyte adenosine 3, 5 -monophosphate and blocks antigenic histamine release. Science 173 743-745. 

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