Adeno-Associated Virus capsid

Ried, M.U., A. Girod, K. Leike, H. Buning, and M. Hallek, Adeno-associated virus capsids displaying immunoglobulin-binding domains permit antibody-mediated vector retargeting to specific cell surface receptors. J Virol, 2002. 76(9) 4559-66. 

The Role of the Adeno-Associated Virus Capsid in Gene Transfer... 

Van Vhet K, Blouin V, Agbandje-McKenna M, Snyder RO. Proteolytic mapping of the adeno-associated virus capsid. Mol Ther 2006 14 809-821. 

Grifman, M., Trepel, M., Speece, P, Gilbert, L.B., Arap, W., Pasquahni, R., Weitzman, M.D., 2001. Incorporahon of tumor-targeting peptides into recombinant adeno-associated virus capsids. Mol. Then 3, 964—975. 

Wu, P, W. Xiao, T. Conlon, I Hnghes, M. Agbandje-McKenna, T. Ferkol, T. Flotte, and N. Muzyczka, Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism. J Virol, 2000. 74(18) 8635 7. 

Girod, A., M. Ried, C. Wobns, H. Lahm, K. Leike, I Kleinschmidt, G. Deleage, and M. Hallek, Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2. Nat Med, 1999. 5(12) 1438. 

Trempe, J. P. and Carter, B. J. (1988). Alternate mRNA splicing is required for synthesis of adeno-associated virus VP1 capsid protein. J. Virol. 62, 3356-3363. 

King, J. A., Dubielzig, R., Grimm, D. and Kleinschmidt, J. A. (2001). DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsids. EMBO J. 20, 3282-3291. 

Shi, W., Arnold, G. S. and Bartlett, J. S. (2001). Insertional mutagenesis of the adeno-associated virus type 2 (AAV2) capsid gene and generation of AAV2 vectors targeted to alternative cell-surface receptors. Hum. Gene Ther. 12, 1697-1711. 

Yan, Z., Zak, R., Luxton, G. W., Ritchie, T. C., Bantel-Schaal, U. and Engel-hardt, J. F. (2002). Ubiquitination of both adeno-associated virus type 2 and 5 capsid proteins affects the transduction efficiency of recombinant vectors. J. Virol. 76, 2043-2053. 

Shayakhmetov, D. M., Carlson, C. A., Stecher, H., Li, Q., Stamatoyannopoulos, G. and Lieber, A. (2002). A high-capacity, capsid-modified hybrid adenovirus/ adeno-associated virus vector for stable transduction of human hematopoietic cells. J. Virol. 76, 1135-1143. 

Yang, G. S. et al. (2002). Virus-mediated transduction of murine retina with adeno-associated virus Effects of viral capsid and genome size. J. Virol. 76 (15), 7651-7660. 

Warrington, K. H., Gorbatyuk, O. S., Harrison, J. K. et al. (2004). Adeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminus. J. Virol. 78(12), 6595-6609. 

Steinbach S, Wistuba A, Bock T, Kleinschmidt JA. Assembly of adeno-associated virus type 2 capsids in vitro. J Gen Virol 1997 78 (Pt 6) 1453-1462. 

Girod A, Wobus CE, Zadoii Z, Ried M, Leike K, Tijssen P, Kleinschmidt JA, Hallek M. The VPl capsid protein of adeno-associated virus type 2 is carrying a phospholipase A2 domain required for virus infectivity. J Gen Virol 2002 83 973-978. 

Broekman ML, Comer LA, Hyman BT, Sena-Esteves M. Adeno-associated virus vectors serotyped with AAV8 capsid are more efficient than AAV-1 or -2 serotypes for widespread gene delivery to the neonatal mouse brain. Neuroscience 2006 138 501-510. 

Grimm D, Pandey K, Nakai H, Storm TA, Kay MA. Liver transduction with recombinant adeno-associated virus is primarily restricted by capsid serotype not vector genotype. J Virol 2006,80 426 39. 

Sommer JM, Smith PH, Parthasarathy S, Isaacs J, Vijay S, Kieran J, Powell SK, McClelland A, Wright JF. Quantification of adeno-associated virus particles and empty capsids by optical density measurement. Mol Ther 2003 7 122-128. 

Kronenberg S, Kleinschmidt JA, Bottcher B. Electron cryo-microscopy and image reconstruction of adeno-associated virus type 2 empty capsids. EMBO Rep 2001 2 997-1002. 

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