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Acute cholinergic syndrom

Organophosphorus insecticides are readily absorbed from skin, mucous membranes, and gut. They inhibit cholinesterases, and patients present with an acute cholinergic syndrome. Symptoms depend in part on... [Pg.511]

CALCIUM CHANNEL BLOCKERS IRINOTECAN Risk oft serum concentrations of irinotecan with nifedipine. No cases of toxicity reported Inhibition of hepatic microsomal enzymes but exact mechanism uncertain at present Watch for symptoms/signs of toxicity (especially diarrhoea, an early manifestation of acute cholinergic syndrome)... [Pg.82]

IMATINIB IRINOTECAN t plasma concentrations of SN-38 (the active metabolite of irinotecan) and t toxicity of irinotecan, e.g. diarrhoea, acute cholinergic syndrome, interstitial pulmonary disease Inhibition of CYP3A4-mediated metabolism of SN-38 Peripheral blood counts should be checked before each course of treatment. Monitor lung function. The recommendation is to 1 dose of irinotecan by 25%... [Pg.313]

Lin CC, Chen JC. Medicinal herb Erycibe Henri Prain ( Ting Kung Teng ) resulting in acute cholinergic syndrome. J Toxicol CUn Toxicol 2002 40(2) 185-7. [Pg.1625]

A number of syndromes have been associated with OP exposure, and these are listed in Table 10.3. Some of these syndromes, notably the acute cholinergic syndrome, are largely caused by acetylcholine aeeumulation, whereas another, organophosphate-induced delayed polyneuropathy (OPIDP), clearly is not. [Pg.55]

In addition to the milder long-term effects of OPs, there may be central effects as a result of the hypoxia that may have occurred during convulsions and possible respiratory insufficiency during an acute cholinergic syndrome. [Pg.172]

The presentation and initial treatment of the characteristic acute cholinergic syndrome following severe OP exposure was considered in earlier chapters. Experience with OP pesticide poisoning has shown that in most cases, the signs and symptoms resolve after about 18 h with continuing anticholinergic and oxime treatment. Ventilation, if it had been required, can be discontinued at this stage. [Pg.173]


See other pages where Acute cholinergic syndrom is mentioned: [Pg.637]    [Pg.315]    [Pg.76]    [Pg.763]    [Pg.202]    [Pg.86]    [Pg.826]    [Pg.52]    [Pg.55]    [Pg.55]    [Pg.56]    [Pg.57]    [Pg.63]    [Pg.173]    [Pg.173]    [Pg.173]   
See also in sourсe #XX -- [ Pg.2 , Pg.39 , Pg.41 ]




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