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Activity Against Cancer Cell Lines

Cytotoxic Activity Against Cancer Cell Lines [Pg.63]

Isoterrestrosin B from the fruits of Tribulus terrestris (136) exhibited cytotoxicity against SK-MEL cells while the steroidal saponins isolated [Pg.64]

On the basis of these experiments, we anticipated that conformationally constrained analogues of our open chain diamides (1 and 2) may increase activity against cancer cell lines. In (3-lactam chemistry, this kind of hypothesis had been tested, and it was established that certain (3-lactams are more effective at lowering cholesterol in human plasma when compared to open-chain substrates [12-15]. Therefore, preparation of (3-lactams of type 3 and related compounds was necessary to investigate a comparative study with diamides 1 and 2. [Pg.352]

Pascu GI, Hotze ACG, Sanchez-Cano C, Kariuki BM, Hannon MJ (2007) Dinuclear ruthenium (II) triple-stranded helicates luminescent supramolecular cylinders that bind and coil DNA and exhibit activity against cancer cell lines. Angew Chem Int Ed Engl 46 4374 -378... [Pg.53]

Cytotoxic Activity Against Cancer Cell Lines. 63... [Pg.45]

It was reported by Bezivin et al. (2004) that (—)-usnic acid, the enantiomer of usnic acid isolated from Cladonia convoluta, showed obvious cytotoxic activities against cancer cell lines, such as murine Lewis lung carcinoma, human chronic... [Pg.167]

Figure 15.9 a) Cisplatin, used as a standard for comparison for antiproliferative activity, b) NHC-silver(i) complexes investigated for their antiproliferative activity against cancer cell lines. [Pg.606]

Barreiro E, Casas JS, Couce MD et al (2010) Dinuclear triphenylphosphinegold(I) sulfanylcarboxylates synthesis, structure and cytotoxic activity against cancer cell lines. J Inorg Biochem 104 551-559... [Pg.460]

Scheme 6.3 illustrates a few of the main structural classes of soft coral compounds. Included in this list are the tubulin interactive agents, eleutherobin 41 and sarcodictyin A 42, which show nanomolar potency against cancer cell lines. Also of interest are the pseudopterosin A 44 terpenoids which reduce inflammation. Two other terpenoids, sarcophytol A 43 and sinulodurin A 45, have shown micromolar activity against BALB/3T3 and mammary epithelial cells respectively. [Pg.189]

It possessed cytotoxicity for six cell lines (IC50 l 100pg/mL) and antitumor effects on human nasopharyngeal cancer (CNE2, SUNE-1) and human liver cancer (BEL-7402) in nude mice. Recently artesunate has been analyzed for its antitumor activity against 55 cell lines.It was most active against leukemia and colon cancer cell lines. It is notable that no CEM leukemia sublines, which are resistant to either doxorubicin, vincristine, methotrexate, or hydroxyurea, showed cross resistance to artesunate. [Pg.223]

Suffness and Douros (3) suggested the following definitions to avoid confusion of terminology. Cytotoxicity is used when compounds or extracts show in vitro (in cells) activity against tumor cell lines. Antitumor or antineoplastic indicates that the materials are effective in vivo (in animals) in experimental systems. Anticancer refers to compounds that are active clinically against human cancer. [Pg.1176]

See other pages where Activity Against Cancer Cell Lines is mentioned: [Pg.485]    [Pg.421]    [Pg.689]    [Pg.990]    [Pg.56]    [Pg.991]    [Pg.607]    [Pg.609]    [Pg.471]    [Pg.401]    [Pg.485]    [Pg.421]    [Pg.689]    [Pg.990]    [Pg.56]    [Pg.991]    [Pg.607]    [Pg.609]    [Pg.471]    [Pg.401]    [Pg.141]    [Pg.348]    [Pg.480]    [Pg.490]    [Pg.220]    [Pg.21]    [Pg.424]    [Pg.1184]    [Pg.450]    [Pg.792]    [Pg.199]    [Pg.218]    [Pg.586]    [Pg.547]    [Pg.134]    [Pg.636]    [Pg.597]    [Pg.246]    [Pg.987]    [Pg.66]    [Pg.212]    [Pg.199]    [Pg.97]    [Pg.62]    [Pg.446]    [Pg.510]   


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Against cancer

Cancer cell lines

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