SEARCH Articles Figures Tables Activation of Substrates with Non-Polar Single Bonds Activation of Substrates with Polar Single Bonds Activation of a Substrate toward Nucleophilic Attack Activation of the carbonyl substrate Active transport of substrate Activity Measurements of Proteinases Using Synthetic Substrates Direct Functionalization via C-H Activation of Heterocyclic Substrates Heterolytic Activation of Substrate Intramolecular C-H Activation of Heterocyclic Substrates Precedents for Metal Activation of Organic Substrates Reactions of Redox-Activated Complexes with Gaseous Substrates Releasing the Spring Cofactor- and Substrate-assisted Activation of Factor IXa Substrate Conformational Transition and the Role of Active Site Residues Substrate activation Surface Activity of Polyethers on Copper and Tin Substrates The Selective Activation of Alternative Reaction Sites in Substrates