Acids n-caproic acid

Myristic acid from hexanoic acid and methyl hydrogen sebacate). Dissolve 23-2 g. of redistilled hexanoic acid (n-caproic acid), b.p. 204-5-205-5°l760 mm., and 21-6 g. of methyl hydrogen sebacate in 200 ml. of absolute methanol to which 0 -13 g. of sodium has been added. Electrolyse at 2-0 amps., whilst maintaining the temperature between 30° and 40°, until the pH is about 8-0 (co. 6 hours). Neutralise the contents of the electrolysis cell with a little acetic acid and distil off the methyl alcohol on a water bath. Dissolve the residue in 200 ml. of ether, wash with three 50 ml. portions of saturated sodium bicarbonate solution, once with water, dry with anhydrous magnesium sulphate, and distil with the aid of a fractionating column (see under Methyl hydrogen adipate). Collect the w-decane at 60°/10 mm. (3-0 g.), the methyl myristate at 158-160°/ 10 mm. (12 - 5g.) and dimethyl hexadecane-1 16-dicarboxylateat 215-230°/ 7 mm. (1 -5 g.)... 

Acids. Acetic acid n-Caproic acid Benzoic acid Phenylacetic acid Succinic acid Adipic acid Anthranilic acid. 

SYNS BUTYLACETIC ACID CAPROIC ACID n-CAPROIC ACID CAPRONIC ACID FEMA No. 2559 HEXACID 698 n-HEXANOIC ACID n-HEXOIC ACID PENTIFORMIC ACID PENTYLFORMIC ACID... 

Synonyms Butylacetic acid n-Caproic acid Capronic acid Carboxylic acid C6 Hexanoic acid 1-Hexanoic acid n-Hexanoic acid Hexoic acid Pentiformic acid Pentylformic acid Empirical CsHijOj... 

CAS 142-62-1 EINECS/ELINCS 205-550-7 UN 1760 UN 2829 (DOT) FEMA 2559 Synonyms Butylacetic acid n-Caproic acid ... 

Fit a reflux condenser into the short neck of a 125 ml. Claisen flask, a separatory funnel into the long neck, and plug the side arm with a small cork (compare Fig. Ill, 31, 1). Place 58 g. (62 ml.) of commercial n-caproic acid (1) in the flask and heat on a water hath. Add 75 g. (46 ml.) of redistilled thionyl chloride through the separatory funnel during 45 minutes shake the flask from time to time to ensure thorough mixing. Reflux the mixture for 30 minutes. Arrange the apparatus for distillation from an air bath (Fig. II, 5, 3) the excess of thionyl chloride passes over flrst, followed by n-caproyl chloride at 145-155° (mainly at 150-155°). The yield of acid chloride is 56 g. 

FIGURE 9 Capillary zone electrophoresis of eight recombinant human anti bod ies/anti body fragments. Capillary BioCAP XL coated capillary (50 pm x 47 cm) 45 mM g-amino-n-caproic acid/ acetic acid, pH 4.5, 0.1% HPMC voltage 30kV, normal polarity capillary temperature 20°C detection, UV at 214 nm. 

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